2,6-Difluoro-N-(2-methoxyethyl)-N-(thiophen-3-ylmethyl)benzenesulfonamide CAS 1219904-36-5
| CAS No. | 1219904-36-5 |
| Molecular Formula | C14H15F2NO3S2 |
| Molecular Weight | 347.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2,6-Difluoro-N-(2-methoxyethyl)-N-(thiophen-3-ylmethyl)benzenesulfonamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2,6-Difluoro-N-(2-methoxyethyl)-N-(thiophen-3-ylmethyl)benzenesulfonamide (CAS 1219904-36-5), a certified reference material (molecular formula C14H15F2NO3S2, MW 347.40 g/mol) for analytical method development and quality control.
2,6-Difluoro-N-(2-methoxyethyl)-N-(thiophen-3-ylmethyl)benzenesulfonamide (C14H15F2NO3S2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2,6-Difluoro-N-(2-methoxyethyl)-N-(thiophen-3-ylmethyl)benzenesulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H15F2NO3S2 |
| Molecular Weight | 347.40 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
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Recommended Standards
- Cefalexin (CAS 15686-71-2)
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- Topramezone Impurity 2 (CAS CATO-C4X-35032)
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- 2-[(2,2,2-trifluoroethyl)sulfanyl]ethan-1-ol (CAS 5187-61-1)
- 3-[(2-Chloroethyl)sulfanyl]oxolane (CAS 1564673-69-3)
- tert-Butyl 4-(6-fluoroquinolin-8-yl)piperazine-1-carboxylate (CAS 796851-14-4)
- 4-(2-Aminoethyl)-6-methylpicolinonitrile (CAS 1393576-26-5)
- 5-Fluoro-2’-O-methyl-4-thiouridine (CAS 869355-51-1)
- Spiro[3H-indole-3,4'-piperidine]-1'-carboxylic acid, 1,2-dihydro-2-oxo-1-(phenylmethyl)-, 1,1-dimethylethyl ester (CAS 293744-34-0)
- 5-Hydroxy-8-methylquinolin-4(1H)-one (CAS 190516-92-8)
- 1-(2-Hydroxyethyl)pyridin-2(1H)-one (CAS 64330-83-2)
- Semaglutide Impurity 162 (x TFA Salt) (CAS CATO-C4X-2226162)
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