3-Chloro-2-fluoropyridine-5-boronic Acid Pinacol Ester CAS 1220219-73-7
| CAS No. | 1220219-73-7 |
| Molecular Formula | C11H14BClFNO2 |
| Molecular Weight | 257.50 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 257.50 g/mol gives 3-Chloro-2-fluoropyridine-5-boronic Acid Pinacol Ester distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-Chloro-2-fluoropyridine-5-boronic Acid Pinacol Ester (CAS 1220219-73-7), molecular formula C11H14BClFNO2 and molecular weight 257.50 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-Chloro-2-fluoropyridine-5-boronic Acid Pinacol Ester (C11H14BClFNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-Chloro-2-fluoropyridine-5-boronic Acid Pinacol Ester under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H14BClFNO2 |
| Molecular Weight | 257.50 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 6-Chloro-5-fluoropyridine-3-boronic Acid Pinacol Ester (CAS 1073312-28-3)
- 2-Chloro-6-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1146615-89-5)
- 2-Chloro-4-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1256359-04-2)
- 5-Chloro-2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1310383-58-4)
- 2-Chloro-3-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1416367-16-2)
- 2-Chloro-5-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1492890-58-0)
- 6-Chloro-2-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1628524-89-9)
- 4-Chloro-2-fluoro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 2223012-68-6)
Recommended Standards
- Ethyl (E)-3-amino-4,4,4-trichloro-2-cyanobut-2-enoate (CAS 112528-71-9)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (2-chloro-3-fluoropyridin-4-yl)boronate (CAS 1029654-43-0)
- 5-bromopyrimidine-2-sulfonyl chloride (CAS 1211591-80-8)
- Gsk3036656 (CAS 2131798-12-2)
- Benzyl (S)-2-(Boc-amino)-5-(dimethylamino)-5-oxopentanoate (CAS 72468-46-3)
- 6,6-Oxybis(3-bromobenzoic acid) (CAS 1311197-85-9)
- 2-(4-(4-Fluorophenyl)-2-methyl-5-oxo-2,5-dihydro-1H-pyrazol-3-yl)-N-isopropylthiazole-4-carboxamide (CAS 914287-34-6)
- 2H-Indol-2-one, 4-[2-(dipropylamino)ethyl]-1,3-dihydro-1-methoxy-, hydrochloride (CAS 1796934-24-1)
- N1-(2-Methylquinolin-6-yl)propane-1,3-diamine (CAS 802302-31-4)
- Labetalol Impurity 46 (CAS CATO-C4X-246646)
- (2R)-2-(chloromethyl)oxetane (CAS 1107646-00-3)
- 1,4-bis(2,2,2-trifluoroethoxy)benzene (CAS 66300-61-6)
- 3-[(pyrimidin-2-ylsulfanyl)methyl]-1-benzofuran-2-carboxylic acid (CAS 1039812-24-2)
- Semaglutide impurity 87 (CAS CATO-C4X-222687)
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