3-Amino-4-(trifluoromethyl)benzonitrile CAS 1220630-83-0
| CAS No. | 1220630-83-0 |
| Molecular Formula | C8H5F3N2 |
| Molecular Weight | 186.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-Amino-4-(trifluoromethyl)benzonitrile (CAS 1220630-83-0), molecular formula C8H5F3N2 and molecular weight 186.13 g/mol, is a CATO reference standard with documented purity and traceability.
3-Amino-4-(trifluoromethyl)benzonitrile (C8H5F3N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 3-Amino-4-(trifluoromethyl)benzonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5F3N2 |
| Molecular Weight | 186.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 4-Amino-1-methyl-5-nitro-1H-pyrazole-3-carboxylic acid (CAS 107259-81-4)
- 2-Amino-5-ethynyl-4-(trifluoromethyl)pyridine (CAS 1321612-90-1)
- 3-Amino-2-(trifluoromethyl)benzonitrile (CAS 1369869-39-5)
- 2-Amino-4-(trifluoromethoxy)butanamide (CAS 1481445-46-8)
- 2-Amino-3-trifluoromethylbenzonitrile (CAS 58458-14-3)
- 2-Amino-5-(trifluoromethyl)benzonitrile (CAS 6526-08-5)
- 2-Amino-6-(trifluoromethyl)benzonitrile (CAS 58458-11-0)
- 3-Amino-5-(trifluoromethyl)benzonitrile (CAS 49674-28-4)
Recommended Standards
- 4-(Trifluoromethyl)-1H-pyrrolo[2,3-c]pyridine (CAS 1211521-88-8)
- 3-(Trifluoromethyl)pyridine-4-acetonitrile (CAS 1227490-44-9)
- 7-(Trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine (CAS 1190316-27-8)
- 4-(Trifluoromethyl)pyridine-3-acetonitrile (CAS 1227514-93-3)
- 5-Phenyl-2,3-dihydro-1H-pyrrolizine-6,7-dicarboxylic acid (CAS 303145-39-3)
- 2-(Quinolin-8-yloxy)-N-(2,2,2-trichloroacetoxy)acetimidamide (CAS 88758-81-0)
- 2-Amino-1-(3,4-difluorophenyl)propane-1,3-diol (CAS 1496789-36-6)
- (+)-Valerianol (CAS 20489-45-6)
- (5-(N,N-dimethylsulfamoyl)-2-methoxyphenyl)boronic acid (CAS 859160-65-9)
- 2-Phenylethenesulfonamide (CAS 4363-41-1)
- 5-Bromo-6-(1H-pyrazol-1-yl)pyridin-3-amine (CAS 1522912-84-0)
- Methyl 2-(2-(2,4-dichlorophenoxy)acetamido)-5-((2-ethoxyphenyl)carbamoyl)-4-methylthiophene-3-carboxylate (CAS 335409-01-3)
- (1R,2R)-2-(3,5-dimethylphenyl)cyclopropane-1-carboxylic acid (CAS 220353-65-1)
- Galanin-Like Peptide (rat) trifluoroacetate salt (CAS 245114-97-0)
Why CATO?
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