3-Amino-5-(trifluoromethyl)benzonitrile CAS 49674-28-4
| CAS No. | 49674-28-4 |
| Molecular Formula | C8H5F3N2 |
| Molecular Weight | 186.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 3-Amino-5-(trifluoromethyl)benzonitrile (CAS 49674-28-4), a certified reference material (molecular formula C8H5F3N2, MW 186.13 g/mol) for analytical method development and quality control.
3-Amino-5-(trifluoromethyl)benzonitrile (C8H5F3N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Amino-5-(trifluoromethyl)benzonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5F3N2 |
| Molecular Weight | 186.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 4-Amino-1-methyl-5-nitro-1H-pyrazole-3-carboxylic acid (CAS 107259-81-4)
- 3-Amino-4-(trifluoromethyl)benzonitrile (CAS 1220630-83-0)
- 2-Amino-5-ethynyl-4-(trifluoromethyl)pyridine (CAS 1321612-90-1)
- 3-Amino-2-(trifluoromethyl)benzonitrile (CAS 1369869-39-5)
- 2-Amino-4-(trifluoromethoxy)butanamide (CAS 1481445-46-8)
- 2-Amino-3-trifluoromethylbenzonitrile (CAS 58458-14-3)
- 2-Amino-5-(trifluoromethyl)benzonitrile (CAS 6526-08-5)
- 2-Amino-6-(trifluoromethyl)benzonitrile (CAS 58458-11-0)
Recommended Standards
- 3-(Trifluoromethyl)benzofuran (CAS 65715-21-1)
- 3-Phenyl-3-(trifluoromethyl)diazirine (CAS 73899-14-6)
- 3-(Trifluoromethyl)-7-azaindole (CAS 892414-47-0)
- 4-(Trifluoromethyl)-1H-benzo[d]imidazole (CAS 392-11-0)
- 5-Bromo-4-methoxy-2-(piperazin-1-yl)pyrimidine (CAS 885267-38-9)
- 4-(aminomethyl)-N-(2-methoxyethyl)aniline (CAS 1221722-17-3)
- Ethyl 4-Methyl-2-pyrrolecarboxylate (CAS 40611-85-6)
- Decanedioic acid, polymer with 2,2'-oxybis[ethanol] and 1,2,3-propanetriol (CAS 63150-11-8)
- Indometacin EP Impurity F (CAS 402849-27-8)
- 2-(2-Chloro-6-nitrophenyl)ethan-1-ol (CAS 102493-68-5)
- tert-Butyl (2S,4R)-rel-4-amino-2-(hydroxymethyl)piperidine-1-carboxylate (CAS 1402249-03-9)
- 2-Bromo-4-(difluoromethyl)-5-methoxypyridine-3-sulfonamide (CAS 1805351-94-3)
- 4-Ethyl-N-((1-(thiophen-2-ylmethyl)piperidin-4-yl)methyl)benzamide (CAS 954079-91-5)
- Tau Peptide (268-282) trifluoroacetate salt (CAS 330456-37-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com