2-Fluoro-5-methylpyrazine CAS 1220799-57-4

Description

The occurrence of 2-Fluoro-5-methylpyrazine is closely related to a nitrile group, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 2-Fluoro-5-methylpyrazine (CAS 1220799-57-4), a certified reference material (molecular formula C5H5FN2, MW 112.11 g/mol) for analytical method development and quality control.

The molecular framework of 2-Fluoro-5-methylpyrazine (C5H5FN2) is characterized by a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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