5-Fluoro-2-methylpyrimidine CAS 54376-50-0
| CAS No. | 54376-50-0 |
| Molecular Formula | C5H5FN2 |
| Molecular Weight | 112.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Fluoro-2-methylpyrimidine is closely related to a nitrile group, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-Fluoro-2-methylpyrimidine (CAS 54376-50-0), molecular formula C5H5FN2 and molecular weight 112.11 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrile group, fluorine substitution, 5-Fluoro-2-methylpyrimidine is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 112.11 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H5FN2 |
| Molecular Weight | 112.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluoro Standards
- 2-Fluoro-5-methylpyrazine (CAS 1220799-57-4)
- 5-Fluoro-4-methylpyrimidine (CAS 1785532-82-2)
- 2-Fluoro-5-methylpyrimidine (CAS 62802-36-2)
- 4-Fluoro-2-methylpyrimidine (CAS 51421-89-7)
- 4-Fluoro-6-methylpyrimidine (CAS 51421-88-6)
- 3-Fluoro-2-hydroxypyridine (CAS 1547-29-1)
- 5-Fluoro-1H-pyrrole-2-carbaldehyde (CAS 156395-08-3)
- 2-Fluoro-3-hydroxypyridine (CAS 174669-74-0)
Recommended Standards
- 5-Fluoropyridin-3-amine (CAS 210169-05-4)
- Hydroxymethanesulfonic acid (CAS 75-92-3)
- 2-Amino-3-fluoropyridine (CAS 21717-95-3)
- 2-Amino-4-fluoropyridine (CAS 944401-77-8)
- Caffeic acid-<SUP>13</SUP>C<SUB>9</SUB> (CAS 1173097-51-2)
- 4-(3,6-Di-tert-butyl-9H-carbazol-9-yl)aniline (CAS 255829-30-2)
- 2-Bromo-5-chloro-3-(difluoromethyl)-6-fluoropyridine (CAS 1804724-44-4)
- 5-Methyl-1H-indazole-3-carbonitrile (CAS 90322-83-1)
- 2-Amino-4-(2-fluorophenyl)butanoic acid (CAS 225233-81-8)
- Apremilast Impurity 80 (CAS 60758-86-3)
- 6-(Tetrahydro-2H-pyran-4-yl)-1,2,3,4-tetrahydropyrido[2,3-d]pyridazin-5(6H)-one (CAS 1447953-16-3)
- 2,2-Difluoro-1-phenyl-1-propanone (CAS 703-17-3)
- 2-(N-(3,5-dichlorophenyl)methylsulfonamido)-n-isobutylacetamide (CAS 493002-01-0)
- (D-His1)-Exenatide trifluoroacetate salt (CAS 1678417-09-8)
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