1-Chloro-2-(difluoromethyl)-3-fluoro-4-methylbenzene CAS 1221272-76-9
| CAS No. | 1221272-76-9 |
| Molecular Formula | C8H6ClF3 |
| Molecular Weight | 194.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-Chloro-2-(difluoromethyl)-3-fluoro-4-methylbenzene is closely related to fluorine/chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-Chloro-2-(difluoromethyl)-3-fluoro-4-methylbenzene (CAS 1221272-76-9), molecular formula C8H6ClF3 and molecular weight 194.58 g/mol, is a CATO reference standard with documented purity and traceability.
1-Chloro-2-(difluoromethyl)-3-fluoro-4-methylbenzene (C8H6ClF3) contains fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-Chloro-2-(difluoromethyl)-3-fluoro-4-methylbenzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6ClF3 |
| Molecular Weight | 194.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- 2-Chloro-6-methylbenzotrifluoride 1-Chloro-3-methyl-2-(trifluoromethyl)benzene 112641-25-5 (CAS 112641-25-5)
- 2-Chloro-4-(1,1-difluoroethyl)-1-fluorobenzene (CAS 1138444-93-5)
- 1-Chloro-3-methyl-5-(trifluoromethyl)benzene (CAS 1214384-22-1)
- 4-Chloro-2-methylbenzotrifluoride (CAS 13630-22-3)
- 1-Chloro-2-(2,2,2-trifluoroethyl)benzene (CAS 145914-05-2)
- 4-Chloro-1-methyl-2-(trifluoromethyl)benzene (CAS 1839-92-5)
- (1-Chloro-2,2,2-trifluoroethyl)benzene (CAS 384-65-6)
- 1-(2-Chloro-1,1-difluoroethyl)-4-fluorobenzene (CAS 2091146-42-6)
Recommended Standards
- 2-(2-Chloroethyl)-1,3,5-trifluorobenzene (CAS 1260764-21-3)
- 5-Chloro-4-(difluoromethoxy)pyridin-2-amine (CAS 2231672-98-1)
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- 5-Chloro-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carbaldehyde (CAS 660845-30-7)
- Tert-butyl (R)-3-hydroxy-3-(trifluoromethyl)piperidine-1-carboxylate (CAS 1670260-03-3)
- 5-Fluoro-2-(pyrrolidin-1-yl)aniline (CAS 869942-11-0)
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- (2-(2,4-Dichlorophenoxy)acetyl)-L-asparticacid (CAS 35144-55-9)
- 4-((2,6-Dichlorobenzyl)oxy)-5-methyl-1-phenyl-3-(trifluoromethyl)-1H-pyrazole (CAS 318949-56-3)
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