1-{[1,1'-Biphenyl]-4-yl}-3-chloropropan-2-one CAS 1221343-04-9
| CAS No. | 1221343-04-9 |
| Molecular Formula | C15H13ClO |
| Molecular Weight | 244.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-{[1,1'-Biphenyl]-4-yl}-3-chloropropan-2-one (C15H13ClO) is characterized by a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies 1-{[1,1'-Biphenyl]-4-yl}-3-chloropropan-2-one (CAS 1221343-04-9), a certified reference material (molecular formula C15H13ClO, MW 244.72 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-{[1,1'-Biphenyl]-4-yl}-3-chloropropan-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H13ClO |
| Molecular Weight | 244.72 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
Related Biphenyl Standards
- ({[1,1'-biphenyl]-2-yl}amino)thiourea (CAS 860609-71-8)
- 1-([1,1'-Biphenyl]-4-yl)-2-nitroethan-1-ol (CAS 126939-80-8)
- [1,1-Biphenyl]-4-carboxylic acid, 4-fluoro-2-hydroxy-, methyl ester (CAS 198994-01-3)
- [1,1'-Biphenyl]-2,2'-diyldimethanethiol (CAS 17749-54-1)
- 42973-13-7 (Biphenyl-4-yloxy)acetyl chloride MFCD11107993 (CAS 42973-13-7)
- (S)-1-([1,1'-Biphenyl]-4-yl)-3-chloropropan-2-ol, 97% (CAS 1573000-28-8)
- [1,1'-Biphenyl]-4-ylchlorodimethylsilane (CAS 41081-31-6)
- 4'-Butyl-[1,1'-biphenyl]-4-thiol (CAS 107336-77-6)
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