5-{[(3,4-dichlorophenyl)methyl]sulfanyl}-2-ethyl-8,9-dimethoxy-[1,2,4]triazolo[1,5-c]quinazoline CAS 1221715-30-5
| CAS No. | 1221715-30-5 |
| Molecular Formula | C20H18Cl2N4O2S |
| Molecular Weight | 449.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-{[(3,4-dichlorophenyl)methyl]sulfanyl}-2-ethyl-8,9-dimethoxy-[1,2,4]triazolo[1,5-c]quinazoline (CAS 1221715-30-5), molecular formula C20H18Cl2N4O2S and molecular weight 449.35 g/mol, is a CATO reference standard with documented purity and traceability.
5-{[(3,4-dichlorophenyl)methyl]sulfanyl}-2-ethyl-8,9-dimethoxy-[1,2,4]triazolo[1,5-c]quinazoline (C20H18Cl2N4O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-{[(3,4-dichlorophenyl)methyl]sulfanyl}-2-ethyl-8,9-dimethoxy-[1,2,4]triazolo[1,5-c]quinazoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H18Cl2N4O2S |
| Molecular Weight | 449.35 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
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Recommended Standards
- Ledipasvir Impurity 17 (CAS CATO-C4X-331317)
- [(2R,3R,4R,5S)-3-(benzoyloxy)-5-bromo-4-fluoro-4-methyloxolan-2-yl]methyl benzoate (CAS 1233335-84-6)
- 2-(4-Benzoylphenyl)-2-(4-bromophenyl)-N-((dimethylamino)methylene)acetamide (CAS 339115-38-7)
- N-(4-phenoxyphenyl)-5,7-bis(trifluoromethyl)-1,8-naphthyridin-2-amine (CAS 241488-37-9)
- [1,1':4',1''-Terphenyl]-3,3'',5,5''-tetraamine (CAS 1374433-06-3)
- (4R)-2-Cyclohexyl-1,3-selenazolidine-4-carboxylic acid (CAS 924636-77-1)
- Dimethyl 4,4'-((1R,2R)-1,2-diaminoethane-1,2-diyl)dibenzoate dihydrochloride (CAS 1055301-09-1)
- Ethyl 5-(Trifluoromethyl)-3-p-tolylisoxazole-4-carboxylate (CAS 1159978-84-3)
- Ethyl 4-(4-cyano-1-methyl-1H-imidazol-5-yl)-1-ethyl-5-nitro-1H-pyrrole-2-carboxylate (CAS 1669415-57-9)
- 4-chloro-2-methyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbaldehyde (CAS 1111237-78-5)
- 4-(Trifluoromethyl)quinoline-2-carbonitrile (CAS 25199-89-7)
- Zonisamide impurity 8 (CAS CATO-C4X-17858)
- 2-(3-Fluorophenyl)-8-methylimidazo[1,2-a]pyridine-3-carbaldehyde (CAS 1048917-19-6)
- D-Phe6-Tirzepatide (CAS CATO-CPTD788925)
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