(3E)-1-[(2,6-Dichlorophenyl)methyl]-3-{[4-(trifluoromethyl)phenyl]imino}-2,3-dihydro-1H-indol-2-one CAS 478031-82-2
| CAS No. | 478031-82-2 |
| Molecular Formula | C22H13Cl2F3N2O |
| Molecular Weight | 449.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (3E)-1-[(2,6-Dichlorophenyl)methyl]-3-{[4-(trifluoromethyl)phenyl]imino}-2,3-dihydro-1H-indol-2-one.
(3E)-1-[(2,6-Dichlorophenyl)methyl]-3-{[4-(trifluoromethyl)phenyl]imino}-2,3-dihydro-1H-indol-2-one (CAS 478031-82-2) is a high-purity analytical reference standard with the molecular formula C22H13Cl2F3N2O and a molecular weight of 449.25 g/mol.
Structurally, (3E)-1-[(2,6-Dichlorophenyl)methyl]-3-{[4-(trifluoromethyl)phenyl]imino}-2,3-dihydro-1H-indol-2-one (C22H13Cl2F3N2O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 449.25 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (3E)-1-[(2,6-Dichlorophenyl)methyl]-3-{[4-(trifluoromethyl)phenyl]imino}-2,3-dihydro-1H-indol-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H13Cl2F3N2O |
| Molecular Weight | 449.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
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