Salbutamol Impurity 75 CAS 1221726-71-1
| CAS No. | 1221726-71-1 |
| Molecular Formula | C17H29NO3 |
| Molecular Weight | 295.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Salbutamol Impurity 75 (CAS 1221726-71-1) is a certified pharmaceutical impurity reference standard with the molecular formula C17H29NO3 and a molecular weight of 295.42 g/mol.
The molecular framework of Salbutamol Impurity 75 (C17H29NO3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C17H29NO3 |
| Molecular Weight | 295.42 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 1 |
Related Salbutamol Standards
- Salbutamol Impurity 58 (CAS CATO-C4X-117658)
- Salbutamol Impurity 64 (CAS CATO-C4X-117664)
- Salbutamol Impurity 96 (CAS 63416-80-8)
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Recommended Standards
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- Fovinaciclib Impurity 3 (CAS CATO-C4X-33863)
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- Medroxyprogesterone impurity 9 (CAS 14510-23-7)
- methyl 2-cyano-2-cyclohexylideneacetate (CAS 55568-06-4)
- (2S)-2-Amino-N-methyl-4-(methylsulfanyl)butanamide (CAS 68800-02-2)
- methyl 2-amino-3-(2,5-dioxopyrrolidin-1-yl)propanoate (CAS 1250538-29-4)
- 11-Methoxy-5-methyl-[1,3]dioxolo[4,5-b]acridin-10(5H)-one (CAS 477-82-7)
- Palmitoyl Hexapeptide-12 TFA salt (CAS 171263-26-6(Free Base))
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