Salbutamol Impurity 220 CAS CATO-C4X-1176220
| CAS No. | CATO-C4X-1176220 |
| Molecular Formula | C11H11BrO4 |
| Molecular Weight | 287.11 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 287.11 g/mol gives Salbutamol Impurity 220 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Salbutamol Impurity 220 (CAS CATO-C4X-1176220), a pharmacopoeial impurity reference standard (molecular formula C11H11BrO4, MW 287.11 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Salbutamol Impurity 220 (C11H11BrO4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Salbutamol Impurity 220 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H11BrO4 |
| Molecular Weight | 287.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
Related Salbutamol Standards
- Salbutamol Impurity 183 (CAS CATO-C4X-1176183)
- Salbutamol Impurity 79 (CAS CATO-C4X-117679)
- Salbutamol Impurity 106 (CAS CATO-C4X-1176106)
- Salbutamol Impurity 223 (CAS CATO-C4X-1176223)
- Salbutamol Impurity 99 (CAS 27475-09-8)
- Salbutamol Impurity 64 (CAS CATO-C4X-117664)
- Salbutamol Impurity 58 (CAS CATO-C4X-117658)
- Salbutamol Impurity 53 (CAS 54208-72-9)
Recommended Standards
- Macitentan Impurity 10 (CAS 149506-35-4)
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- Evocalcet Impurity 43 (CAS 870859-14-6)
- Dabigatran Impurity 116 (CAS CATO-C4X-1089116)
- Meclozine Dihydrochloride EP Impurity C (CAS 134-85-0)
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- 6-(Cyanomethyl)-3-(difluoromethyl)-5-methoxypicolinonitrile (CAS 1805288-03-2)
- 2-Cyclopropyl-5-methoxybenzoic acid (CAS 1250297-02-9)
- 1-(3,5-Dichlorophenyl)-4-(difluoromethyl)-1H-1,2,3-triazole (CAS 916151-05-8)
- Insulin Degludec Impurity 14 (CAS CATO-C4X-215714)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com