4-Bromo-2-(((3,5-difluorobenzyl)amino)methyl)phenol CAS 1223889-75-5
| CAS No. | 1223889-75-5 |
| Molecular Formula | C14H12BrF2NO |
| Molecular Weight | 328.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, 4-Bromo-2-(((3,5-difluorobenzyl)amino)methyl)phenol is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 328.15 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
4-Bromo-2-(((3,5-difluorobenzyl)amino)methyl)phenol (CAS 1223889-75-5) is a high-purity analytical reference standard with the molecular formula C14H12BrF2NO and a molecular weight of 328.15 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Bromo-2-(((3,5-difluorobenzyl)amino)methyl)phenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H12BrF2NO |
| Molecular Weight | 328.15 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
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Recommended Standards
- 2-((Bromodifluoromethyl)sulfonyl)benzo[d]thiazole (CAS 1230154-56-9)
- 4-((3,5-Dichloro-2-hydroxybenzyl)amino)-2-hydroxybenzoic acid (CAS 1181226-02-7)
- Ethyl 5-amino-1-(2,4-dichlorobenzoyl)-1H-pyrazole-4-carboxylate (CAS 124281-80-7)
- Axitinib Impurity N25 (CAS 1266386-30-4)
- N-(3-Amino-4-chlorophenyl)-2-(2-methylphenoxy)-butanamide (CAS 1020054-72-1)
- 1-(2-(2-(Cyclobutylamino)pyridin-3-yl)piperidin-1-yl)ethanone (CAS 1352511-57-9)
- (1-(5-Bromo-2-methoxybenzyl)-1H-1,2,3-triazol-4-yl)methanol (CAS 1457914-62-3)
- 1-(4-Methylbenzyl)piperidine (CAS 35278-95-6)
- 1-(Ethoxycarbonyl)-2-[(ethoxycarbonyl)thio]-N,N-dimethyl-L-histidine Methyl Ester (CAS 162138-72-9)
- N1-(tert-Butyl)-N2-(3-(4-(dimethylamino)phenyl)propyl)oxalamide (CAS 954242-41-2)
- 3-(1,4-Diazepan-1-yl)pyrazine-2-carbonitrile (CAS 874815-88-0)
- 2-(Imidazo[1,2-a]pyridin-2-yl)cyclopropane-1-carboxylic acid (CAS 1486072-04-1)
- 1-(4-Fluorobenzyl)piperidine-4-carboxylic acid hydrochloride (CAS 1185088-82-7)
- Xenopsin-Related Peptide 2 (XP-2) (H-9340.0005) (CAS 117442-29-2)
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