3-{[3-(4-Methylphenyl)-1,2,4-oxadiazol-5-yl]methyl}quinazoline-2,4(1H,3H)-dione CAS 1223889-81-3
| CAS No. | 1223889-81-3 |
| Molecular Formula | C18H14N4O3 |
| Molecular Weight | 334.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-{[3-(4-Methylphenyl)-1,2,4-oxadiazol-5-yl]methyl}quinazoline-2,4(1H,3H)-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 3-{[3-(4-Methylphenyl)-1,2,4-oxadiazol-5-yl]methyl}quinazoline-2,4(1H,3H)-dione (CAS 1223889-81-3), a certified reference material (molecular formula C18H14N4O3, MW 334.33 g/mol) for analytical method development and quality control.
The molecular framework of 3-{[3-(4-Methylphenyl)-1,2,4-oxadiazol-5-yl]methyl}quinazoline-2,4(1H,3H)-dione (C18H14N4O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H14N4O3 |
| Molecular Weight | 334.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 4 |
Related Methylphenyl Standards
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- 4-[(4-Methylphenyl)carbamoyl]phenyl N,N-dimethylsulfamate (CAS 338396-30-8)
- n-[2-(3-methylphenyl)ethyl]-3-(2-oxo-1,2-dihydroquinolin-3-yl)propanamide (CAS 1328653-50-4)
- (E)-[(4-Methylphenyl)methoxy]({[2-(phenylsulfanyl)pyridin-3-yl]methylidene})amine (CAS 478031-09-3)
- 1-(4-Methylphenyl)-4-phenyl-3-[(piperidin-1-yl)methyl]azetidin-2-one (CAS 551921-50-7)
- N-(4-{[(4-methylphenyl)sulfanyl]methyl}phenyl)benzamide (CAS 338398-71-3)
- 4-((2-Ethyl-6-methylphenyl)amino)-2-(4-methylpiperazin-1-yl)-4-oxobutanoic acid (CAS 899964-43-3)
Recommended Standards
- 6-(1,3-Dimethyl-1H-pyrazol-4-yl)-3-phenylisoxazolo[5,4-b]pyridine-4-carboxylic acid (CAS 1171701-49-7)
- 2-(5-Methoxy-2-methyl-1H-indol-3-yl)-7-nitro-quinoxaline (CAS 1380571-57-2)
- (4-Oxo-3,4-dihydroquinazolin-2-yl)methyl 2H-chromene-3-carboxylate (CAS 1110816-75-5)
- 7-Ethoxy-N-(3-ethynylphenyl)-6-nitroquinazolin-4-amine (CAS 1430203-53-4)
- (S)-2-Amino-3-(2-methoxyphenyl)propan-1-ol (CAS 938462-32-9)
- 4-chloro-2-(difluoromethyl)-6-fluoro-pyridine-3-carbonyl chloride (CAS 1823934-47-9)
- Avibactam Impurity 49 (CAS 288-31-3)
- 3-(4-Ethylphenyl)-2-methylbutanoic acid (CAS 1525422-42-7)
- Methyl 2-methyl-5-(trifluoromethyl)-1H-indole-3-carboxylate (CAS 1313752-95-2)
- Perospirone Impurity 19 (CAS 117307-09-2)
- 4-Bromo-2-(((2,4,5-trifluorophenyl)amino)methyl)phenol (CAS 868256-54-6)
- 6,7-Dihydro-5H-pyrrolo[2,1-c][1,2,4]triazole-3-carboxamide (CAS 108800-61-9)
- methyl 4-bromo-3-methylthieno[2,3-c]pyridine-2-carboxylate (CAS 870244-28-3)
- Acetyl Hexapeptide-38 (CAS 1400634-44-7)
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