2-(Chloromethyl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-9-carboxylic acid CAS 1224166-25-9
| CAS No. | 1224166-25-9 |
| Molecular Formula | C10H7ClN2O3 |
| Molecular Weight | 238.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-(Chloromethyl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-9-carboxylic acid (CAS 1224166-25-9), a certified reference material (molecular formula C10H7ClN2O3, MW 238.63 g/mol) for analytical method development and quality control.
The molecular framework of 2-(Chloromethyl)-4-oxo-4H-pyrido[1,2-a]pyrimidine-9-carboxylic acid (C10H7ClN2O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H7ClN2O3 |
| Molecular Weight | 238.63 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- 1-(4-chlorophenyl)-5-oxo-2,5-dihydro-1H-pyrazole-3-carboxylic acid (CAS 1206134-81-7)
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- 5-Amino-3-(2-chlorophenyl)isoxazole-4-carboxylic acid (CAS 132066-40-1)
- 5-Cyclopropoxy-N,N-dimethyl-4-(methylthio)picolinamide (CAS 1243467-58-4)
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- N-(5-Amino-2-methylphenyl)-2-methoxybenzamide (CAS 926200-62-6)
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- 2-methoxy-1-(quinolin-5-yl)ethan-1-one (CAS 1513089-61-6)
- 4-Chloro-2-methylbenzotrifluoride (CAS 13630-22-3)
- 2-(3-Hydroxycyclobutyl)-2-methylpropanoic acid (CAS 2252276-38-1)
- N-[4-(Heptyloxy)benzyl]-3-(phenethyloxy)aniline (CAS 1040682-24-3)
- 4-(1-phenylpropyl)pyrrolidin-2-one (CAS 1824461-43-9)
- Semaglutide impurity 201 (CAS CATO-C4X-2226201)
Why CATO?
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