8-(Chloromethyl)-6H-[1,3]dioxolo[4,5-g]chromen-6-one CAS 484000-52-4
| CAS No. | 484000-52-4 |
| Molecular Formula | C11H7ClO4 |
| Molecular Weight | 238.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
8-(Chloromethyl)-6H-[1,3]dioxolo[4,5-g]chromen-6-one (CAS 484000-52-4) is a high-purity analytical reference standard with the molecular formula C11H7ClO4 and a molecular weight of 238.62 g/mol.
Structurally, 8-(Chloromethyl)-6H-[1,3]dioxolo[4,5-g]chromen-6-one (C11H7ClO4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 238.62 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 8-(Chloromethyl)-6H-[1,3]dioxolo[4,5-g]chromen-6-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H7ClO4 |
| Molecular Weight | 238.62 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
Related Chloromethyl Standards
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Recommended Standards
- 6-Chloro-7-methyl-4-oxo-4h-chromene-2-carboxylic acid (CAS 262590-94-3)
- Methyl 6-chloro-2-oxo-2H-chromene-3-carboxylate (CAS 91058-98-9)
- 6-Chloro-4-hydroxy-7-methyl-2-oxo-2H-chromene-3-carbaldehyde (CAS 925005-58-9)
- Methyl 6-chloro-4-oxo-4h-chromene-2-carboxylate (CAS 27455-31-8)
- Insulin Pork(≥27 USP units/mg) (CAS 12584-58-6)
- 8-Chloro-[1,3]dioxolo[4,5-g]quinazoline (CAS 72700-23-3)
- 2-Bromo-1-(3-fluoro-2-hydroxyphenyl)ethanone (CAS 1621375-68-5)
- 5-Methyl-1-propyl-1H-imidazole (CAS 144748-27-6)
- 2-Chloro-4-(methylthio)-1,3,5-triazine (CAS 61810-07-9)
- Ethyl 5-aminospiro[2.3]hexane-1-carboxylate (CAS 1373028-53-5)
- 2-Chloroethyl trifluoromethanesulfonate (CAS 73323-80-5)
- 6-Bromo-3-cyclopropoxy-2-iodopyridine (CAS 1243326-15-9)
- 2-(4-Chlorophenyl)-5-(2-{[(4-methylphenyl)methyl]sulfanyl}phenyl)-1,3,4-oxadiazole (CAS 339104-15-3)
- Tirzepatide Impurity 13 (CAS CATO-C4X-324013)
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