N-(2-chloropyridin-3-yl)-5-methyl-2-nitrobenzamide CAS 1225-84-9
| CAS No. | 1225-84-9 |
| Molecular Formula | C13H10ClN3O3 |
| Molecular Weight | 291.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, N-(2-chloropyridin-3-yl)-5-methyl-2-nitrobenzamide (C13H10ClN3O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 291.69 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
N-(2-chloropyridin-3-yl)-5-methyl-2-nitrobenzamide (CAS 1225-84-9) is a high-purity analytical reference standard with the molecular formula C13H10ClN3O3 and a molecular weight of 291.69 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(2-chloropyridin-3-yl)-5-methyl-2-nitrobenzamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H10ClN3O3 |
| Molecular Weight | 291.69 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
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- 2-(3-Chloropyridin-2-yl)-5-(trifluoromethyl)-2H-1,2,3-triazole-4-carboxylic acid (CAS 1431729-85-9)
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Recommended Standards
- 2'-Chloro-4'-methyl-5-nitro-[1,1'-biphenyl]-3-carboxylic acid (CAS 1261967-52-5)
- 2-((4-Chlorobenzyl)oxy)-5-nitrobenzaldehyde (CAS 114483-64-6)
- 3'-Chloro-4'-methyl-3-nitro-[1,1'-biphenyl]-4-carboxylic acid (CAS 1261979-62-7)
- Roflumilast Impurity 49 (CAS CATO-C4X-108449)
- MEthyl 2-chloro-5-(dimethylamino)benzoate (CAS 137548-16-4)
- 3-Phenyl-2-thioxo-6-(trifluoromethyl)-2,3-dihydropyrimidin-4(1H)-one (CAS 269736-23-4)
- 1'-benzylspiro[1,3-benzoxazine-2,4'-piperidin]-4(3H)-one (CAS 54906-22-8)
- 2-Ethyl-4-ethynylpyridine (CAS 1215782-60-7)
- 2-Chloro-1-(tetrahydro-2H-pyran-3-yl)ethan-1-one (CAS 1425865-56-0)
- N-allyl-2-(N-phenylphenylsulfonamido)acetamide (CAS 339103-00-3)
- (3R,4S,5S,6S)-6-(fluoromethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol (CAS 34168-77-9)
- [3-(4-bromophenyl)-1H-1,2,4-triazol-5-yl]methanamine hydrochloride (CAS 1240527-78-9)
- Ethyl 7-(3,4-dimethoxyphenyl)-2-methyl-4-(4-methyl-3-nitrophenyl)-5-oxo-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate (CAS 503591-61-5)
- Hepcidin/LEAP-1 (Human); Liver-Expressed Antimicrobial Peptide (CAS 342790-21-0)
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