2-(3-Chloropyridin-2-yl)-5-(trifluoromethyl)-2H-1,2,3-triazole-4-carboxylic acid CAS 1431729-85-9
| CAS No. | 1431729-85-9 |
| Molecular Formula | C9H4ClF3N4O2 |
| Molecular Weight | 292.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(3-Chloropyridin-2-yl)-5-(trifluoromethyl)-2H-1,2,3-triazole-4-carboxylic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-(3-Chloropyridin-2-yl)-5-(trifluoromethyl)-2H-1,2,3-triazole-4-carboxylic acid (CAS 1431729-85-9), a certified reference material (molecular formula C9H4ClF3N4O2, MW 292.60 g/mol) for analytical method development and quality control.
2-(3-Chloropyridin-2-yl)-5-(trifluoromethyl)-2H-1,2,3-triazole-4-carboxylic acid (C9H4ClF3N4O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(3-Chloropyridin-2-yl)-5-(trifluoromethyl)-2H-1,2,3-triazole-4-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H4ClF3N4O2 |
| Molecular Weight | 292.60 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloropyridin Standards
- 2-(5-Chloropyridin-2-yl)-5-(trifluoromethyl)-2H-1,2,3-triazole-4-carboxylic acid (CAS 1708168-28-8)
- 2-(2-Chloropyridin-3-yl)-5-(trifluoromethyl)-2H-1,2,3-triazole-4-carboxylic acid (CAS 1779132-42-1)
- N-[(6-Chloropyridin-3-yl)methoxy]-2-methoxybenzamide (CAS 866020-44-2)
- 2-(((6-Chloropyridin-3-yl)methyl)thio)benzo[d]thiazole (CAS 821782-43-8)
- ((6-Chloropyridin-3-yl)methyl)zinc pivalate (0.65 mmol/g) (CAS 1383708-40-4)
- n-(3-((3-Chloropyridin-4-yl)amino)propyl)-N-ethylmethanesulfonamide (CAS 1427568-00-0)
- 2-{[(5-chloropyridin-2-yl)carbamoyl]amino}benzoic acid (CAS 1146289-92-0)
- N-(2-chloropyridin-3-yl)-5-methyl-2-nitrobenzamide (CAS 1225-84-9)
Recommended Standards
- 3-Chloro-2-(4-nitro-1h-pyrazol-1-yl)-5-(trifluoromethyl)pyridine (CAS 122890-61-3)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2H-1,2,3-triazole-4-carboxylic acid (CAS 1431729-92-8)
- 1-(6-Chloropyridazin-3-yl)-5-(trifluoromethyl)-1h-pyrazole-4-carboxylic acid (CAS 1171703-24-4)
- 1-((2-Bromo-5-chlorobenzyl)amino)-2-methylpropan-2-ol (CAS 1478813-99-8)
- 67992-58-9 HQ43CN02U9 Ioxaglate sodium [USAN] Ioxaglic acid sodium Hexabrix Benzoic acid, 3-((((3-(acetylmethylamino)-2,4,6-triiodo-5-((methylamino)carbonyl)benzoyl)amino)acetyl)amino)-5-(((2-hydroxyethyl)amino)carbonyl)-2,4,6-triiodo-, monosodium salt Benzoic acid, 3-((((3-(acetylmethylamino)-2,4,6-triiodo-5-((methylamino)carbonyl)benzoyl)amino)acetyl)amino)-5-(((2-hydroxyethyl)amino)carbonyl)-2,4,6-triiodo-, sodium salt Sodium 3-((((3-(acetylmethylamino)-2,4,6-triiodo-5-((methylamino)carbonyl)benzoyl)amino)acetyl)amino)-5-(((2-hydroxyethyl)amino)carbonyl)-2,4,6-triiodobenzoate EINECS 268-060-2 Sodium N-(2-hydroxyethyl)-2,4,6-triiodo-5-(2-(2,4,6-triiodo-3-(N-methylacetamido)-5-(methylcarbamoyl)benzamido)acetamido)isophthalamate Ioxaglate sodium UNII-HQ43CN02U9 Sodium ioxaglate (CAS 67992-58-9)
- 5-Nitro-2-(piperazin-1-yl)benzoic acid (CAS 168123-39-5)
- N-(3-Chlorophenyl)-6-phenyl-2-(pyridin-3-yl)pyrimidine-4-carboxamide (CAS 860787-58-2)
- 10-Acetyl-1,1,7,7-tetramethyl-2,3,6,7-tetrahydro-1H-pyrano[2,3-f]pyrido[3,2,1-ij]quinolin-11(5H)-one (CAS 114768-72-8)
- (4-[3-(Trifluoromethyl)phenoxy]phenyl)boranediol (CAS 958457-42-6)
- 3-(((2R,3R,4S,5R,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)propane-1,2-diyl distearate (CAS 41670-62-6)
- 2-((4-(N-carbamimidoylsulfamoyl)phenyl)carbamoyl)benzoic acid (CAS 40265-97-2)
- 1H-Pyrazolo[4,3-d]pyrimidine, 3-bromo-1-ethyl- (CAS 1357143-39-5)
- (2-Methoxy-5-methylphenyl)(pyridin-2-yl)methanol (CAS 1284479-83-9)
- Copper Peptide ·2 acetate salt (CAS 130120-57-9)
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