6-Chloro-5-fluoro-1H-indole CAS 122509-72-2
| CAS No. | 122509-72-2 |
| Molecular Formula | C8H5ClFN |
| Molecular Weight | 169.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Chloro-5-fluoro-1H-indole.
CATO supplies 6-Chloro-5-fluoro-1H-indole (CAS 122509-72-2), a certified reference material (molecular formula C8H5ClFN, MW 169.58 g/mol) for analytical method development and quality control.
Based on its molecular formula C8H5ClFN, 6-Chloro-5-fluoro-1H-indole contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 169.58 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-Chloro-5-fluoro-1H-indole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5ClFN |
| Molecular Weight | 169.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 7-Chloro-4-fluoro-1H-indole (CAS 1000341-60-5)
- 4-Chloro-7-fluoro-1h-indole (CAS 1000341-78-5)
- 4-Chloro-2-fluoro-5-methylbenzonitrile (CAS 1126424-34-7)
- 4-Chloro-2-fluoro-3-methylbenzonitrile (CAS 1207875-88-4)
- 5-Chloro-7-fluoro-1H-indole (CAS 1227499-38-8)
- 2-Chloro-2-(2-fluorophenyl)acetonitrile (CAS 1247740-42-6)
- 5-Chloro-2-fluoro-1H-indole (CAS 1354220-70-4)
- 5-Chloro-3-fluoro-2-methylbenzonitrile (CAS 1365969-38-5)
Recommended Standards
- 2-(4-chlorophenyl)-2-fluoroacetonitrile (CAS 106468-05-7)
- 4-Cyano-3-fluorobenzyl chloride (CAS 1260814-48-9)
- 2-(Chloromethyl)-3-fluorobenzonitrile (CAS 1260814-51-4)
- 5-(Chloromethyl)-2-fluorobenzonitrile (CAS 1260892-59-8)
- tert-Butyl (5-bromo-2-(hydroxymethyl)phenyl)carbamate (CAS 1664374-88-2)
- 6-(3,5-Dimethylphenyl)nicotinaldehyde (CAS 924817-87-8)
- Pyrimidine-5(4H)-thione (CAS 220560-98-5)
- N-(Thiophen-3-ylmethyl)-N-(2,2,2-trifluoroethyl)pyrazine-2-carboxamide (CAS 1235049-87-2)
- N-(2-Ethylhexyl)-4-nitrobenzamide (CAS 154702-08-6)
- 3-Amino-n'-hydroxypropanimidamide (CAS 16750-43-9)
- (4-Fluoro-2,3-dihydrobenzo[b]thiophen-2-yl)methanamine (CAS 1039984-17-2)
- 2-Methyltetracosanoic acid (CAS 62764-46-9)
- 3,3,4,4-Tetrafluorobenzophenone (CAS 117320-03-3)
- (β-Asp5)-Delta-Sleep Inducing Peptide (CAS 82602-88-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com