7-Chloro-5-phenyl-2-(p-tolyl)oxazolo[4,5-d]pyrimidine CAS 1225162-95-7
| CAS No. | 1225162-95-7 |
| Molecular Formula | C18H12ClN3O |
| Molecular Weight | 321.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 7-Chloro-5-phenyl-2-(p-tolyl)oxazolo[4,5-d]pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
7-Chloro-5-phenyl-2-(p-tolyl)oxazolo[4,5-d]pyrimidine (CAS 1225162-95-7) is a high-purity analytical reference standard with the molecular formula C18H12ClN3O and a molecular weight of 321.76 g/mol.
7-Chloro-5-phenyl-2-(p-tolyl)oxazolo[4,5-d]pyrimidine (C18H12ClN3O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C18H12ClN3O |
| Molecular Weight | 321.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- Methyl 2-{[(5-chloro-1,3-dimethyl-1H-pyrazol-4-yl)carbonyl]amino}-2-phenylacetate (CAS 1096440-16-2)
- N-(3-Chloro-4-methylphenyl)-3-(6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)propanamide (CAS 1105202-77-4)
- 2-chloro-8-methyl-3-(5-phenyl-1,2,4-oxadiazol-3-yl)quinoline (CAS 1142201-67-9)
- 3-(2-Chloro-7-methylquinolin-3-yl)-5-phenyl-1,2,4-oxadiazole (CAS 1142201-73-7)
- 7-Chloro-2-phenyl-5-(p-tolyl)oxazolo[4,5-d]pyrimidine (CAS 1241709-22-7)
- 1-(5-Chloro-2-methoxyphenyl)-3-(2-(dimethylamino)pyrimidin-5-yl)urea (CAS 1396873-69-0)
- Ethyl 5-chloro-6-((4-methoxybenzyl)amino)pyrimidine-4-carboxylate (CAS 1415562-75-2)
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Recommended Standards
- (3AR,4S,6R,6aS)-6-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxole-4-carbaldehyde (CAS 1379540-71-2)
- Ethyl 2-[1-(3-chlorophenyl)-3,5-dimethyl-1h-pyrazol-4-yl]-2-(n-hydroxyimino)acetate (CAS 1006482-03-6)
- (2E)-2-(4-chlorobenzenesulfonyl)-3-(4-fluorophenyl)prop-2-enenitrile 691367-43-8 MS-11282 (CAS 691367-43-8)
- 4-Chloro-2-(4-(ethoxycarbonyl)-1,5-dimethyl-1H-pyrrol-2-yl)benzoic acid (CAS 1644543-61-2)
- 2-Chloro-4-cyclopropoxypyridine (CAS 1209458-93-4)
- 4-(Bromomethyl)-3,4'-bipyridine (CAS 1227589-07-2)
- 4-((3-(Trifluoromethyl)pyridin-2-yl)oxy)aniline (CAS 1086378-47-3)
- 2-((4-Amino-5-oxo-4,5-dihydro-1,2,4-triazin-3-yl)thio)-N-(6-methylbenzo[d]thiazol-2-yl)acetamide (CAS 869068-56-4)
- 2-((4-(4-(Tert-butyl)phenyl)-3-cyano-6-phenylpyridin-2-yl)thio)-N-(p-tolyl)acetamide (CAS 332127-85-2)
- 5-(Bromomethyl)-2,1,3-benzothiadiazole (CAS 65858-50-6)
- 1-(3-Chlorophenyl)ethylamine (CAS 24358-43-8)
- Isochroman-7-ol (CAS 1391209-22-5)
- 2-((4-(Tert-butyl)cyclohexyl)amino)propan-1-ol (CAS 1153893-60-7)
- Des-Gly34-Tirzepatide (CAS CATO-CPTD788940)
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