Ethyl 5-chloro-6-((4-methoxybenzyl)amino)pyrimidine-4-carboxylate CAS 1415562-75-2
| CAS No. | 1415562-75-2 |
| Molecular Formula | C15H16ClN3O3 |
| Molecular Weight | 321.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Ethyl 5-chloro-6-((4-methoxybenzyl)amino)pyrimidine-4-carboxylate (CAS 1415562-75-2), molecular formula C15H16ClN3O3 and molecular weight 321.76 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Ethyl 5-chloro-6-((4-methoxybenzyl)amino)pyrimidine-4-carboxylate (C15H16ClN3O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H16ClN3O3 |
| Molecular Weight | 321.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Ethyl Standards
- Methyl 2-{[(5-chloro-1,3-dimethyl-1H-pyrazol-4-yl)carbonyl]amino}-2-phenylacetate (CAS 1096440-16-2)
- N-(3-Chloro-4-methylphenyl)-3-(6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)propanamide (CAS 1105202-77-4)
- 2-chloro-8-methyl-3-(5-phenyl-1,2,4-oxadiazol-3-yl)quinoline (CAS 1142201-67-9)
- 3-(2-Chloro-7-methylquinolin-3-yl)-5-phenyl-1,2,4-oxadiazole (CAS 1142201-73-7)
- 7-Chloro-5-phenyl-2-(p-tolyl)oxazolo[4,5-d]pyrimidine (CAS 1225162-95-7)
- 7-Chloro-2-phenyl-5-(p-tolyl)oxazolo[4,5-d]pyrimidine (CAS 1241709-22-7)
- 1-(5-Chloro-2-methoxyphenyl)-3-(2-(dimethylamino)pyrimidin-5-yl)urea (CAS 1396873-69-0)
- 3-(2-Chloro-6-methylquinolin-3-yl)-5-phenyl-1,2,4-oxadiazole (CAS 1431728-48-1)
Recommended Standards
- (3AR,4S,6R,6aS)-6-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxole-4-carbaldehyde (CAS 1379540-71-2)
- 4-Chloro-2-(4-(ethoxycarbonyl)-1,5-dimethyl-1H-pyrrol-2-yl)benzoic acid (CAS 1644543-61-2)
- 1-(2-Chlorophenyl)-3-(4-(dimethylamino)-2-methoxypyrimidin-5-yl)urea (CAS 1797659-87-0)
- N-(3-Chlorophenyl)-3-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 196504-86-6)
- 2-[2-(4-chloro-1H-pyrazol-1-yl)ethoxy]aniline (CAS 1182977-83-8)
- methyl 5-({[amino(imino)methyl]thio}methyl)-2-furoate hydrochloride (CAS 108989-46-4)
- 2-(2-(Hydroxymethyl)pyrrolidin-1-yl)nicotinonitrile (CAS 1249597-28-1)
- 2,5-Dimethyl-<SUP>13</SUP>C<SUB>2</SUB>-furan (CAS 111946-46-4)
- Clevidipine Impurity 35 (CAS CATO-C4X-101535)
- Methyl 3-(pyrimidin-2-yloxy)thiophene-2-carboxylate (CAS 339105-43-0)
- 2-Cyclopropoxy-3-ethyl-N,N-dimethylaniline (CAS 1243403-00-0)
- (Z)-3-((4-chlorophenyl)sulfonyl)-4-(pyrimidin-2-ylamino)but-3-en-2-one (CAS 882259-74-7)
- 1-(6-(Indolin-1-yl)pyridin-3-yl)propan-1-ol (CAS 1355177-98-8)
- Des-His(1)-Semaglutide (CAS CATO-C4X-2226216)
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