[2-(2-Chlorobenzyl)-1,3-thiazol-4-yl]acetic acid CAS 1225504-35-7

Purity 97%+In StockPharmaceutical Standards
CAS No.1225504-35-7
Molecular FormulaC12H10ClNO2S
Molecular Weight267.73 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

[2-(2-Chlorobenzyl)-1,3-thiazol-4-yl]acetic acid CAS 1225504-35-7 chemical structure

Description

[2-(2-Chlorobenzyl)-1,3-thiazol-4-yl]acetic acid (CAS 1225504-35-7) is a high-purity analytical reference standard with the molecular formula C12H10ClNO2S and a molecular weight of 267.73 g/mol.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, [2-(2-Chlorobenzyl)-1,3-thiazol-4-yl]acetic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 267.73 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC12H10ClNO2S
Molecular Weight267.73 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentCl-containing
Nitrogen Atoms1
Sulfur Atoms1

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