N-((1H-Benzo[d]imidazol-2-yl)methyl)-2-(2-((6-methylpyridin-2-yl)amino)thiazol-4-yl)acetamide CAS 1226439-78-6
| CAS No. | 1226439-78-6 |
| Molecular Formula | C19H18N6OS |
| Molecular Weight | 378.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
N-((1H-Benzo[d]imidazol-2-yl)methyl)-2-(2-((6-methylpyridin-2-yl)amino)thiazol-4-yl)acetamide (CAS 1226439-78-6) is a high-purity analytical reference standard with the molecular formula C19H18N6OS and a molecular weight of 378.45 g/mol.
The molecular framework of N-((1H-Benzo[d]imidazol-2-yl)methyl)-2-(2-((6-methylpyridin-2-yl)amino)thiazol-4-yl)acetamide (C19H18N6OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H18N6OS |
| Molecular Weight | 378.45 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 1 |
Recommended Standards
- Ethyl (2-(4-(5-(furan-2-yl)-1,3,4-thiadiazol-2-yl)piperidin-1-yl)acetyl)glycinate (CAS 1226435-08-0)
- Ethyl 3-((4-(m-tolyl)piperazin-1-yl)sulfonyl)-1H-pyrazole-4-carboxylate (CAS 1260947-96-3)
- N-(1-(Benzo[d]thiazol-2-yl)-3-methyl-1H-pyrazol-5-yl)-2-(o-tolyloxy)acetamide (CAS 1172434-00-2)
- 1-((5-Cyclopentyl-1,2,4-oxadiazol-3-yl)methyl)-3-(pyrrolidin-1-ylsulfonyl)pyridin-2(1H)-one (CAS 1396875-74-3)
- (1R,5S)-9-methyl-3,9-diazabicyclo[3.3.1]Nonan-7-amine (CAS 166171-16-0)
- 4051-66-5 167726JT6B 1,3-Dioctadecylurea N,N'-Dioctadecylurea UNII-167726JT6B (CAS 4051-66-5)
- 4-chloro-3-{[(oxolan-2-yl)methyl]sulfamoyl}benzoic acid (CAS 59210-70-7)
- 4-Iodo-N-(thiazol-2-yl)benzenesulfonamide (CAS 148901-09-1)
- 2-Bromo-N-(4-(N-(2,6-dimethylpyrimidin-4-yl)sulfamoyl)phenyl)hexanamide (CAS 380467-37-8)
- Ethyl 1-[cyano(phenyl)methyl]-piperidine-4-carboxylate (CAS 1208220-88-5)
- 17-Hydroxy heptadecanoic acid (CAS 13099-34-8)
- 2-(Aminomethyl)-4-(difluoromethyl)-5-hydroxypyridine-3-acetic acid (CAS 1805994-25-5)
- n-(2-(Pyridin-2-yl)ethyl)tetrahydro-2h-thiopyran-3-amine (CAS 1310244-77-9)
- Semaglutide Impurity 138 (CAS CATO-C4X-2226138)
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