2-Bromo-N-(4-(N-(2,6-dimethylpyrimidin-4-yl)sulfamoyl)phenyl)hexanamide CAS 380467-37-8
| CAS No. | 380467-37-8 |
| Molecular Formula | C18H23BrN4O3S |
| Molecular Weight | 455.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Bromo-N-(4-(N-(2,6-dimethylpyrimidin-4-yl)sulfamoyl)phenyl)hexanamide is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-Bromo-N-(4-(N-(2,6-dimethylpyrimidin-4-yl)sulfamoyl)phenyl)hexanamide (CAS 380467-37-8), molecular formula C18H23BrN4O3S and molecular weight 455.37 g/mol, is a CATO reference standard with documented purity and traceability.
2-Bromo-N-(4-(N-(2,6-dimethylpyrimidin-4-yl)sulfamoyl)phenyl)hexanamide (C18H23BrN4O3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Bromo-N-(4-(N-(2,6-dimethylpyrimidin-4-yl)sulfamoyl)phenyl)hexanamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H23BrN4O3S |
| Molecular Weight | 455.37 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Bromo Standards
- 2-(2-(2-(2-Bromo-4-(tert-butyl)phenoxy)acetyl)hydrazine-1-carbonyl)cyclohexane-1-carboxylic acid (CAS 671795-42-9)
- 8-Bromo-2-(methylthio)-4-((4-phenoxyphenyl)amino)pyrido[4,3-d]pyrimidin-5(6H)-one (CAS 1300611-33-9)
- 5-Bromo-2-(4-fluorophenyl)-N-methyl-6-(N-methylmethylsulfonamido)benzofuran-3-carboxamide (CAS 1333225-20-9)
- N-(2-Bromo-4,6-difluorophenyl)-2-((4-ethyl-5-(pyrazin-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 578699-95-3)
- Ethyl 8-bromo-2-(bromomethyl)-3-methyl-4,5-dioxo-4,5-dihydro-3H-benzo[e]indole-1-carboxylate (CAS 125365-59-5)
- 4-Bromo-2-(tert-butyl)-7-(dimethoxymethyl)-6-iodooxazolo[4,5-c]pyridine (CAS 1305325-14-7)
- 1-Bromo-2-(2,6-difluoro-4-(trifluoromethyl)phenoxy)-3-fluoro-4-(trifluoromethoxy)benzene (CAS 2244085-02-5)
- 10-Bromo-1,1,1,2,2,3,3,4,4,5,5,6,6-tridecafluoro-decane (CAS 181997-60-4)
Recommended Standards
- 1, 4-PREGNADIEN-9α, 11β-DICHLORO-17, 21-DIOL-3, 20-DIONE 21-ACETATE (CAS 79-61-8)
- 2-Hydroxy-2-methyl-3-[3-(trifluoromethyl)benzenesulfonyl]-N-[3-(trifluoromethyl)phenyl]propanamide (CAS 339275-77-3)
- (2S,3S,4S,5R,6S)-2-(methoxycarbonyl)-6-(2-nitrophenoxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate (CAS 55274-44-7)
- 2-Hydroxy-2-methyl-3-[3-(trifluoromethyl)benzenesulfonyl]-N-[4-(trifluoromethyl)phenyl]propanamide (CAS 338956-14-2)
- PRO-LAD (CAS 65527-63-1)
- 2-((2-Bromophenoxy)methyl)-1,3-dioxolane (CAS 850348-70-8)
- Methyl 1-Oxoisoindoline-5-carboxylate (CAS 926307-72-4)
- alpha-Aminothiazole-4-acetic Acid (CAS 50499-25-7)
- 1,6-Dimethyl-1H-benzo[d][1,3]oxazin-2(4H)-one (CAS 1696777-45-3)
- Aciclovir EP Impurity B Hydrochloride (CAS 635-39-2)
- 2-(3-Chlorophenyl)cyclopropanecarboxylic Acid (CAS 91552-11-3)
- Ethyl 4-cyano-5-{2-[(3-cyano-6-methyl-5,6,7,8-tetrahydro-1,6-naphthyridin-2-yl)sulfanyl]acetamido}-3-methylthiophene-2-carboxylate (CAS 488793-00-6)
- (1,10-Phenanthroline)(1,2-octanediolato)Pd(II) (CAS 1219966-88-7)
- D-Thr5-Tirzepatide (CAS CATO-CPTD788926)
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