3-(Pyrrolidin-1-yl)-6-(4-((2-(trifluoromethyl)phenyl)sulfonyl)piperazin-1-yl)pyridazine CAS 1226440-85-2
| CAS No. | 1226440-85-2 |
| Molecular Formula | C19H22F3N5O2S |
| Molecular Weight | 441.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(Pyrrolidin-1-yl)-6-(4-((2-(trifluoromethyl)phenyl)sulfonyl)piperazin-1-yl)pyridazine is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-(Pyrrolidin-1-yl)-6-(4-((2-(trifluoromethyl)phenyl)sulfonyl)piperazin-1-yl)pyridazine (CAS 1226440-85-2) is a high-purity analytical reference standard with the molecular formula C19H22F3N5O2S and a molecular weight of 441.47 g/mol.
The molecular framework of 3-(Pyrrolidin-1-yl)-6-(4-((2-(trifluoromethyl)phenyl)sulfonyl)piperazin-1-yl)pyridazine (C19H22F3N5O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-(Pyrrolidin-1-yl)-6-(4-((2-(trifluoromethyl)phenyl)sulfonyl)piperazin-1-yl)pyridazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H22F3N5O2S |
| Molecular Weight | 441.47 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Pyrrolidin Standards
- 2-[6-(pyrrolidin-1-yl)-2,4-bis(trifluoromethyl)imidazo[1,2-a]1,8-naphthyridin-8-yl]-1,3,4-oxadiazole (CAS 1431424-65-5)
- 1-((R)-pyrrolidin-2-ylmethyl)-3-((S)-quinolin-4-yl((1R,2S,4S,5R)-5-vinylquinuclidin-2-yl)methyl)thiourea (CAS 1222966-43-9)
- 2-Oxo-2-((4-(pyrrolidin-1-ylsulfonyl)phenyl)amino)ethyl 2-(methylthio)nicotinate (CAS 475055-38-0)
- 1-(4-(4-(1-(Pyrrolidin-1-ylsulfonyl)piperidine-4-carbonyl)piperazin-1-yl)phenyl)ethan-1-one (CAS 1428356-46-0)
- 6,9-Bis((2-(pyrrolidin-1-yl)ethyl)amino)benzo[g]isoquinoline-5,10-dione (CAS 144510-91-8)
- 6-(3-(Pyrrolidin-1-yl)propoxy)-2-(4-(3-(pyrrolidin-1-yl)propoxy)phenyl)benzo[d]oxazole (CAS 1219925-73-1)
- 6-Phenyl-2-((2-(pyrrolidin-1-yl)ethyl)thio)-4-(trifluoromethyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile (CAS 664994-25-6)
- 2-(5-Methyl-2-((4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)amino)pyrimidin-4-yl)benzo[b]thiophene-5-carbonitrile (CAS 1138474-61-9)
Recommended Standards
- (2S)-N1-[4-Methyl-5-[2-(2,2,2-trifluoro-1,1-dimethylethyl)-4-pyridinyl]-2-thiazolyl]-1,2-pyrrolidinedicarboxamide (CAS 1217486-61-7)
- 7-Acetamido-6-(benzyloxy)-2-phenylhexahydropyrano[3,2-d][1,3]dioxin-8-yl acetate (CAS 13343-64-1)
- Aztreonam-d6 (CAS 1127452-94-1)
- (2S,4S)-4-{4-[(Benzyloxy)carbonyl]phenoxy}-1-(tert-butoxycarbonyl)-2-pyrrolidinecarboxylic acid (CAS 1354487-27-6)
- 5-bromo-4-fluoro-1H-pyridin-2-one (CAS 1805590-93-5)
- 2-Methyl-N-(2-(pyridin-2-yl)ethyl)pentan-1-amine (CAS 1038282-63-1)
- N-(3-Aminophenyl)-3-isopropoxybenzamide (CAS 1020054-51-6)
- Ethyl 2-(2-methoxy-4-methylphenyl)thiazole-4-carboxylate (CAS 886368-30-5)
- CAS CATO-C3D-262674 (CAS CATO-C3D-262674)
- N-(2-Fluoro-4-methylphenyl)-3-methylbenzamide (CAS 1038042-42-0)
- Esmolol Impurity 24 (CAS CATO-C4X-189124)
- Tucatinib Impurity 10 (CAS CATO-C4X-260510)
- (S)-3-(Trifluoromethyl)-7,7a,8,9,10,11-hexahydro-6H-pyrazino[1,2-d]pyrido[3,2-b][1,4]oxazepine (CAS 2817668-75-8)
- Semaglutide impurity 78 (CAS CATO-C4X-222678)
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