2-(5-Methyl-2-((4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)amino)pyrimidin-4-yl)benzo[b]thiophene-5-carbonitrile CAS 1138474-61-9
| CAS No. | 1138474-61-9 |
| Molecular Formula | C26H25N5OS |
| Molecular Weight | 455.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(5-Methyl-2-((4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)amino)pyrimidin-4-yl)benzo[b]thiophene-5-carbonitrile is closely related to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-(5-Methyl-2-((4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)amino)pyrimidin-4-yl)benzo[b]thiophene-5-carbonitrile (CAS 1138474-61-9) is a high-purity analytical reference standard with the molecular formula C26H25N5OS and a molecular weight of 455.57 g/mol.
The molecular framework of 2-(5-Methyl-2-((4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)amino)pyrimidin-4-yl)benzo[b]thiophene-5-carbonitrile (C26H25N5OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(5-Methyl-2-((4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)amino)pyrimidin-4-yl)benzo[b]thiophene-5-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C26H25N5OS |
| Molecular Weight | 455.57 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Methyl Standards
- 6-(3-(Pyrrolidin-1-yl)propoxy)-2-(4-(3-(pyrrolidin-1-yl)propoxy)phenyl)benzo[d]oxazole (CAS 1219925-73-1)
- 1-(4-(4-(1-(Pyrrolidin-1-ylsulfonyl)piperidine-4-carbonyl)piperazin-1-yl)phenyl)ethan-1-one (CAS 1428356-46-0)
- 2-[6-(pyrrolidin-1-yl)-2,4-bis(trifluoromethyl)imidazo[1,2-a]1,8-naphthyridin-8-yl]-1,3,4-oxadiazole (CAS 1431424-65-5)
- 3-(Pyrrolidin-1-yl)-6-(4-((2-(trifluoromethyl)phenyl)sulfonyl)piperazin-1-yl)pyridazine (CAS 1226440-85-2)
- 1-((R)-pyrrolidin-2-ylmethyl)-3-((S)-quinolin-4-yl((1R,2S,4S,5R)-5-vinylquinuclidin-2-yl)methyl)thiourea (CAS 1222966-43-9)
- 2-Oxo-2-((4-(pyrrolidin-1-ylsulfonyl)phenyl)amino)ethyl 2-(methylthio)nicotinate (CAS 475055-38-0)
- 6,9-Bis((2-(pyrrolidin-1-yl)ethyl)amino)benzo[g]isoquinoline-5,10-dione (CAS 144510-91-8)
- 6-Phenyl-2-((2-(pyrrolidin-1-yl)ethyl)thio)-4-(trifluoromethyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile (CAS 664994-25-6)
Recommended Standards
- 5-[(2,5-Dimethylphenyl)methyl]-7-(morpholine-4-sulfonyl)-1H,2H,3H,3aH,4H,5H-pyrrolo[1,2-a]quinoxalin-4-one (CAS 1042134-66-6)
- (R)-4-benzyl-3-((S)-3-cyclopentyl-2-(4-(methylsulfonyl)phenyl)propanoyl)oxazolidin-2-one (CAS 300355-20-8)
- tert-Butyl (2S,4R)-2-({[(4-methylbenzene)sulfonyl]oxy}methyl)-4-(oxan-2-yloxy)pyrrolidine-1-carboxylate (CAS 2140298-83-3)
- 3-(3,5-Bis(trifluoromethyl)phenyl)-N-((2,3,3-trichloroacryloyl)oxy)acrylimidamide (CAS 646989-56-2)
- 4-(2,4-Difluorophenoxy)-2-((4-methylbenzyl)thio)-5,6,7,8-tetrahydroquinazoline (CAS 672951-71-2)
- 2,4-Dichloro-6-methoxyquinolin-7-ol (CAS 1846571-97-8)
- 3-Chloro-4-methoxybenzimidamide (CAS 102151-35-9)
- Methyl 4-isopropoxythiophene-2-carboxylate (CAS 1707581-76-7)
- 2-(Methylthio)pyrido[2,3-d]pyrimidin-4(3H)-one hydrochloride (CAS 126728-17-4)
- 2-3-4-6-Tetra-O-benzoyl-β-D-glucopyranosyl cyanide (CAS 286369-05-9)
- Methyl (4-bromobenzyl)(methyl)carbamate (CAS 1250211-24-5)
- 3-((1-Methoxypropan-2-yl)oxy)azetidine (CAS 1343311-68-1)
- (E)-{[3-(4-fluorophenyl)-1H-pyrazol-4-yl]methylidene}[(4-fluorophenyl)methoxy]amine (CAS 477711-35-6)
- Calcitonin C-Terminal Flanking Peptide (human) XTFA (CAS 85916-47-8（free base）)
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