(6-Fluoro-1h-indazol-3-yl)methanamine CAS 1226442-91-6
| CAS No. | 1226442-91-6 |
| Molecular Formula | C8H8FN3 |
| Molecular Weight | 165.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), (6-Fluoro-1h-indazol-3-yl)methanamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
(6-Fluoro-1h-indazol-3-yl)methanamine (CAS 1226442-91-6), molecular formula C8H8FN3 and molecular weight 165.17 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (6-Fluoro-1h-indazol-3-yl)methanamine (C8H8FN3) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H8FN3 |
| Molecular Weight | 165.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Fluoro Standards
- 4-Fluoro-2-methyl-1H-pyrrolo[2,3-b]pyridin-5-amine (CAS 1036963-09-3)
- 6-Fluoro-5-methyl-1H-indazol-3-amine (CAS 1037206-99-7)
- 6-Fluoro-2-methylimidazo[1,2-a]pyridin-3-amine (CAS 1344240-97-6)
- 7-Fluoro-N-methyl-1H-benzo[d]imidazol-2-amine (CAS 1352227-22-5)
- 6-fluoro-N-methyl-1H-1,3-benzodiazol-2-amine (CAS 1352227-31-6)
- 2-Fluoro-4-(1-methylhydrazinyl)benzonitrile (CAS 1357626-46-0)
- (7-Fluoro-1H-indazol-3-yl)methanamine (CAS 1360892-81-4)
- 4-(2-Fluoro-2-propyl)pyrimidine-5-carbonitrile (CAS 1427195-26-3)
Recommended Standards
- 2-Amino-4-fluoro-1-methylbenzimidazole (CAS 1183473-03-1)
- 2-Amino-6-fluoro-1-methylbenzimidazole (CAS 1248916-44-0)
- 2-Amino-5-fluoro-1-methylbenzimidazole (CAS 1156928-67-4)
- (R)-Isothiazolidine-3-carboxylic acid 1,1-dioxide (CAS 1311255-12-5)
- (2E)-3-(4-Chlorophenyl)-1-(4-fluorophenyl)prop-2-en-1-one (CAS 28081-12-1)
- 4-(4-Chlorophenyl)-6-(4-(trifluoromethyl)phenyl)-4,5-dihydropyridazin-3(2H)-one (CAS 478260-86-5)
- 1-(1-(Tert-butoxycarbonyl)piperidin-3-yl)-5-methyl-1h-1,2,3-triazole-4-carboxylic acid (CAS 1334493-08-1)
- 2-(2-Aminophenyl)-4H-3,1-benzoxazin-4-one (CAS 7265-24-9)
- 2,5-Dihydrothiophene (CAS 1708-32-3)
- 2-(6-Bromo-1h-indol-1-yl)-1-(pyrrolidin-1-yl)ethan-1-one (CAS 1081145-06-3)
- N-Acetyl-4-aminobiphenyl-d5 (CAS 1217046-73-5)
- Diethyl 4,6-dihydroxyisophthalate (CAS 52959-29-2)
- 2-[(4-Methylbenzyl)oxy]benzoic acid (CAS 52803-45-9)
- Calcitonin N-Terminal Flanking Peptide (human) (CAS 118277-01-3)
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