(R)-Isothiazolidine-3-carboxylic acid 1,1-dioxide CAS 1311255-12-5

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

(R)-Isothiazolidine-3-carboxylic acid 1,1-dioxide (CAS 1311255-12-5), molecular formula C4H7NO4S and molecular weight 165.17 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of (R)-Isothiazolidine-3-carboxylic acid 1,1-dioxide (C4H7NO4S) is characterized by a carbohydrate-derived structure, an amide group, a sulfone group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

As a certified reference material (CRM), (R)-Isothiazolidine-3-carboxylic acid 1,1-dioxide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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