2-(4-Fluorophenyl)-6-(trifluoromethyl)nicotinaldehyde CAS 1227582-90-2

Purity 97%+In StockPharmaceutical Standards
CAS No.1227582-90-2
Molecular FormulaC13H7F4NO
Molecular Weight269.19 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(4-Fluorophenyl)-6-(trifluoromethyl)nicotinaldehyde CAS 1227582-90-2 chemical structure

Description

The occurrence of 2-(4-Fluorophenyl)-6-(trifluoromethyl)nicotinaldehyde is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

2-(4-Fluorophenyl)-6-(trifluoromethyl)nicotinaldehyde (CAS 1227582-90-2) is a high-purity analytical reference standard with the molecular formula C13H7F4NO and a molecular weight of 269.19 g/mol.

Structurally, 2-(4-Fluorophenyl)-6-(trifluoromethyl)nicotinaldehyde (C13H7F4NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 269.19 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(4-Fluorophenyl)-6-(trifluoromethyl)nicotinaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC13H7F4NO
Molecular Weight269.19 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentF-containing
Nitrogen Atoms1

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