5-(4-methylbenzamido)-2-(phenylamino)thiazole-4-carboxamide CAS 1228280-29-2

Description

The molecular framework of 5-(4-methylbenzamido)-2-(phenylamino)thiazole-4-carboxamide (C18H16N4O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

5-(4-methylbenzamido)-2-(phenylamino)thiazole-4-carboxamide (CAS 1228280-29-2), molecular formula C18H16N4O2S and molecular weight 352.41 g/mol, is a CATO reference standard with documented purity and traceability.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-(4-methylbenzamido)-2-(phenylamino)thiazole-4-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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