2-(5-Chloro-2-oxo-2,3-dihydro-1h-indol-3-yl)acetic acid CAS 1228552-97-3
| CAS No. | 1228552-97-3 |
| Molecular Formula | C10H8ClNO3 |
| Molecular Weight | 225.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(5-Chloro-2-oxo-2,3-dihydro-1h-indol-3-yl)acetic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-(5-Chloro-2-oxo-2,3-dihydro-1h-indol-3-yl)acetic acid (CAS 1228552-97-3) is a high-purity analytical reference standard with the molecular formula C10H8ClNO3 and a molecular weight of 225.63 g/mol.
2-(5-Chloro-2-oxo-2,3-dihydro-1h-indol-3-yl)acetic acid (C10H8ClNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H8ClNO3 |
| Molecular Weight | 225.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- Ethyl 7-chloro-1H-pyrazolo[4,3-B]pyridine-6-carboxylate (CAS 100478-04-4)
- 5-(5-chloro-2-methoxyphenyl)-1,3,4-oxadiazol-2-amine (CAS 1016686-46-6)
- Ethyl 5-chloro-3H-imidazo[4,5-b]pyridine-2-carboxylate (CAS 1044772-75-9)
- Ethyl 2-chloro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate (CAS 1060816-62-7)
- ethyl 6-chloro-1H-pyrazolo[3,4-b]pyridine-3-carboxylate (CAS 1083181-27-4)
- 5-Chloro-1,3-dimethyl-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-2,4-dione (CAS 112734-83-5)
- Methyl 4-chloro-2-cyano-5-methoxybenzoate (CAS 1138220-78-6)
- Methyl 6-chloro-8-methylimidazo[1,2-b]pyridazine-3-carboxylate (CAS 1150566-87-2)
Recommended Standards
- 2-(4-Chloro-7-hydroxy-1H-indol-3-yl)acetic acid (CAS 1227599-55-4)
- Ethyl 5-chloroimidazo[1,5-a]pyrazine-1-carboxylate (CAS 1250996-90-7)
- 4-Chloro-5-hydroxyindole-3-acetic acid (CAS 1227599-47-4)
- Ethyl 6-Chloroimidazo[1,2-a]pyrazine-3-carboxylate (CAS 1250996-97-4)
- 2,2,3,4,4,4-Hexafluorobutyl acrylate 1h,1h,3h-hexafluorobutyl acrylate acrylic acid 2,2,3,4,4,4-hexafluoro-butyl ester HFBA 54052-90-3 (CAS 54052-90-3)
- 4-ethynylpyrimidin-2-amine (CAS 1207175-18-5)
- Benzyl ((1-(2-aminoacetyl)pyrrolidin-2-yl)methyl)(methyl)carbamate (CAS 1353946-70-9)
- 4-((2-Hydroxy-3,5-diiodobenzylidene)amino)-3-(pyridin-2-yl)-1H-1,2,4-triazole-5(4H)-thione (CAS 613248-51-4)
- 2-[2-(Piperazin-1-yl)-ethyl]-1,3-dioxolan (CAS 25553-77-9)
- 1-(3-Fluoro-5-methylphenyl)piperazine (CAS 1402672-60-9)
- Nimodipine Impurity 18 (CAS CATO-C4X-138518)
- Palonosetron Impurity 16 (CAS 177793-80-5)
- 3-Chloro-N-[2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl]propanamide (CAS 1365963-00-3)
- Amyloid Precursor Frameshift Mutant C-Terminal Peptide trifluoroacetate salt (CAS 189125-14-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com