Palonosetron Impurity 16 CAS 177793-80-5

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.177793-80-5
Molecular FormulaC18H26N2
Molecular Weight270.41 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Palonosetron Impurity 16 CAS 177793-80-5 chemical structure

Description

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO supplies Palonosetron Impurity 16 (CAS 177793-80-5), a pharmacopoeial impurity reference standard (molecular formula C18H26N2, MW 270.41 g/mol) used for the identification and quantification of trace impurities in APIs.

Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, Palonosetron Impurity 16 is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 270.41 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC18H26N2
Molecular Weight270.41 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2007
Nitrogen Atoms2

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