5-(Trifluoromethyl)-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine CAS 1228666-22-5
| CAS No. | 1228666-22-5 |
| Molecular Formula | C17H25F3N2Si |
| Molecular Weight | 342.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(Trifluoromethyl)-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine.
CATO supplies 5-(Trifluoromethyl)-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1228666-22-5), a certified reference material (molecular formula C17H25F3N2Si, MW 342.47 g/mol) for analytical method development and quality control.
The molecular framework of 5-(Trifluoromethyl)-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine (C17H25F3N2Si) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-(Trifluoromethyl)-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H25F3N2Si |
| Molecular Weight | 342.47 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Trifluoromethyl Standards
- 4-(Trifluoromethyl)-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1092579-99-1)
- [4-phenyl-5-(trifluoromethyl)-2-thienyl]methyl pivalate (CAS 256525-65-2)
- 4-Methyl-5-{2-[3-(trifluoromethyl)phenyl]-1,3-thiazol-4-yl}-4H-1,2,4-triazole-3-thiol (CAS 400083-67-2)
- 6-((3-(Trifluoromethyl)benzyl)thio)imidazo[2,1-b]thiazole-5-carbaldehyde (CAS 303996-46-5)
- 4-((4-Phenyl-6-(trifluoromethyl)pyrimidin-2-yl)thio)butanoic acid (CAS 514180-40-6)
- 4-Methyl-2-[3-(trifluoromethyl)benzenesulfonyl]-5H,6H,7H-cyclopenta[d]pyrimidine (CAS 339019-67-9)
- Ethyl 2-((5-(3-(trifluoromethyl)phenyl)pyrimidin-2-yl)thio)acetate (CAS 339101-32-5)
- 2-(Trifluoromethyl)-5-(4-(trifluoromethyl)phenyl)furan-3-carbonyl chloride (CAS 240122-23-0)
Recommended Standards
- Pregna-1,4-diene-3-one, 17,20-dihydroxy-6-methylene (CAS 1204325-02-9)
- (4Z,7Z,10Z,13Z,15E,19Z)-17-Oxodocosa-4,7,10,13,15,19-hexaenoic acid (CAS 1233715-28-0)
- Carbic Anhydride (CAS 129-64-6)
- Anacardic acid C15:3 (CAS 103904-73-0)
- 2-(Bromomethyl)-6-nitroquinoline (CAS 90767-09-2)
- 2,4,6-Trimethyl-3-(5-methyl-4-phenylisoxazol-3-yl)benzenesulfonamide (CAS 775344-85-9)
- 2,5-Dichloro-6-methoxy-3-(trifluoromethyl)pyridine (CAS 188555-18-2)
- 3-Methyl-5-(p-tolyl)isoxazole-4-carboxylic acid (CAS 91569-57-2)
- 2-(2-((tert-Butoxycarbonyl)amino)ethyl)-5-methylthiazole-4-carboxylic acid (CAS 2095670-49-6)
- Tert-butyl 2-(2-methyl-6-oxo-1,6-dihydropyridin-3-yl)piperidine-1-carboxylate (CAS 1352524-53-8)
- (4-Bromophenyl)(3-(methylthio)phenyl)methanol (CAS 1443342-97-9)
- 2-((5-Bromopyridin-2-yl)oxy)ethan-1-amine (CAS 29450-02-0)
- Hydrocortamate (CAS 76-47-1)
- Peptide Impurity 26 (CAS 1350456-66-4)
Why CATO?
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