2-(Trifluoromethyl)-5-(4-(trifluoromethyl)phenyl)furan-3-carbonyl chloride CAS 240122-23-0
| CAS No. | 240122-23-0 |
| Molecular Formula | C13H5ClF6O2 |
| Molecular Weight | 342.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(Trifluoromethyl)-5-(4-(trifluoromethyl)phenyl)furan-3-carbonyl chloride.
2-(Trifluoromethyl)-5-(4-(trifluoromethyl)phenyl)furan-3-carbonyl chloride (CAS 240122-23-0) is a high-purity analytical reference standard with the molecular formula C13H5ClF6O2 and a molecular weight of 342.62 g/mol.
2-(Trifluoromethyl)-5-(4-(trifluoromethyl)phenyl)furan-3-carbonyl chloride (C13H5ClF6O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H5ClF6O2 |
| Molecular Weight | 342.62 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
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- [4-phenyl-5-(trifluoromethyl)-2-thienyl]methyl pivalate (CAS 256525-65-2)
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- 6-((3-(Trifluoromethyl)benzyl)thio)imidazo[2,1-b]thiazole-5-carbaldehyde (CAS 303996-46-5)
- 4-((4-Phenyl-6-(trifluoromethyl)pyrimidin-2-yl)thio)butanoic acid (CAS 514180-40-6)
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Recommended Standards
- (R)-9-bromo-10-chloro-1,2,3,4,12,12a-hexahydro-6H-benzo[f]pyrazino[2,1-c][1,4]oxazepine-8-carbonitrile (CAS 2487480-32-8)
- Palbociclib Impurity 25 (CAS 1016636-76-2)
- Rhodium tribromide (CAS 15608-29-4)
- 8-Chloro-2-(5-chloro-2-thienyl)quinoline-4-carbonyl chloride (CAS 1160256-92-7)
- 9-Benzyl-6-iodo-9H-purine (CAS 83135-13-1)
- methyl 2-(3-azabicyclo[3.1.0]hexan-6-yl)acetate (CAS 1782845-59-3)
- Ethyl 1,4-dimethyl-1H-imidazole-2-carboxylate (CAS 898834-09-8)
- 5-Amino-6-(4-(pentyloxy)phenyl)pyridazin-3(2H)-one (CAS 122322-99-0)
- 4-Chloro-5-methyl-1H-indazole-3-carboxylic acid (CAS 1500464-25-4)
- 1-(4-Bromo-2-fluorobenzyl)-4-methyl-1,4-diazepane (CAS 1291624-13-9)
- 3-(5-(2-Chlorophenyl)furan-2-yl)acrylic acid (CAS 58110-39-7)
- (R)-4-(Amino(cyclopropyl)methyl)benzonitrile (CAS 1212935-89-1)
- N,N-dimethyl-2-oxo-1,2-dihydrobenzo[cd]indole-6-sulfonamide (CAS 53257-01-5)
- Semaglutide impurity 106 (CAS CATO-C4X-2226106)
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