1-(6-(3-(((Tert-butyldimethylsilyl)oxy)methyl)pyrrolidin-1-yl)-2-fluoropyridin-3-yl)ethan-1-one CAS 1228666-50-9
| CAS No. | 1228666-50-9 |
| Molecular Formula | C18H29FN2O2Si |
| Molecular Weight | 352.52 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(6-(3-(((Tert-butyldimethylsilyl)oxy)methyl)pyrrolidin-1-yl)-2-fluoropyridin-3-yl)ethan-1-one (C18H29FN2O2Si) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 1-(6-(3-(((Tert-butyldimethylsilyl)oxy)methyl)pyrrolidin-1-yl)-2-fluoropyridin-3-yl)ethan-1-one (CAS 1228666-50-9), a certified reference material (molecular formula C18H29FN2O2Si, MW 352.52 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H29FN2O2Si |
| Molecular Weight | 352.52 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Tert Standards
- (3-(4-((Tert-butyldimethylsilyl)oxy)piperidin-1-yl)-5-fluorophenyl)boronic acid (CAS 1704073-45-9)
- 3-(1-(tert-Butyldimethylsilyl)-1H-indol-5-yl)benzoic acid (CAS 1228957-08-1)
- (6-((tert-Butyldimethylsilyl)oxy)-2,5,7,8-tetramethylchroman-2-yl)methanol (CAS 228114-44-1)
- 6-(3-(((Tert-butyldimethylsilyl)oxy)methyl)pyrrolidin-1-yl)-2-fluoronicotinic acid (CAS 1228666-21-4)
- 2-(((tert-Butyldimethylsilyl)oxy)methyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine (CAS 2766346-94-3)
- 2-(8-(((tert-Butyldimethylsilyl)oxy)methyl)-6-fluoroisoquinolin-5-yl)acetic acid (CAS 2842055-54-1)
- 3-(((Tert-butyldimethylsilyl)oxy)methyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1310383-10-8)
- 2-(((tert-Butyldimethylsilyl)oxy)methyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 1351378-73-8)
Recommended Standards
- Dibucaine-d9 Hydrochloride (CAS 1215713-38-4)
- 1,7-Dibenzyl-1,4,7,10-tetraazacyclododecane (CAS 156970-79-5)
- N'-tert-Butyl-N-(2,6-diisopropyl-4-phenoxyphenyl)formimidamide (CAS 169337-81-9)
- Gadobutrol Impurity 127 (CAS 216101-03-0)
- N,N-Diethyl-N'-(6-methyl-1,3-benzothiazol-2-yl)ethane-1,2-diamine (CAS 854085-13-5)
- Methyl 3-amino-5-phenylpentanoate (CAS 129042-97-3)
- Sodium (5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl phosphate (CAS 107132-16-1)
- Tropicamide Impurity 21 (CAS 96392-48-2)
- 1-(2-Chlorobenzyl)piperidin-3-ol (CAS 414890-85-0)
- Methyl 3-fluoroisoquinoline-6-carboxylate (CAS 1241675-07-9)
- Methyl 5-(((1-formylnaphthalen-2-yl)oxy)methyl)furan-2-carboxylate (CAS 438221-05-7)
- (S)-2-methoxy-1-(3,4,5-trifluorophenyl)ethan-1-amine (CAS 1269938-12-6)
- 3,5-Dimethylbenzenesulfonohydrazide (CAS 1249159-79-2)
- [y-Glu3]-Semaglutide Impurity 135 (CAS CATO-C4X-2226135)
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