2-(8-(((tert-Butyldimethylsilyl)oxy)methyl)-6-fluoroisoquinolin-5-yl)acetic acid CAS 2842055-54-1

Purity 97%+In StockPharmaceutical Standards
CAS No.2842055-54-1
Molecular FormulaC18H24FNO3Si
Molecular Weight349.47 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(8-(((tert-Butyldimethylsilyl)oxy)methyl)-6-fluoroisoquinolin-5-yl)acetic acid CAS 2842055-54-1 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(8-(((tert-Butyldimethylsilyl)oxy)methyl)-6-fluoroisoquinolin-5-yl)acetic acid.

CATO supplies 2-(8-(((tert-Butyldimethylsilyl)oxy)methyl)-6-fluoroisoquinolin-5-yl)acetic acid (CAS 2842055-54-1), a certified reference material (molecular formula C18H24FNO3Si, MW 349.47 g/mol) for analytical method development and quality control.

2-(8-(((tert-Butyldimethylsilyl)oxy)methyl)-6-fluoroisoquinolin-5-yl)acetic acid (C18H24FNO3Si) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC18H24FNO3Si
Molecular Weight349.47 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2003
Halogen ContentF-containing
Nitrogen Atoms1

Related tert Standards

Recommended Standards

Why CATO?