2-Amino-4-(trifluoromethyl)pyridine-3-acetonitrile CAS 1228898-39-2
| CAS No. | 1228898-39-2 |
| Molecular Formula | C8H6F3N3 |
| Molecular Weight | 201.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-Amino-4-(trifluoromethyl)pyridine-3-acetonitrile (CAS 1228898-39-2), a certified reference material (molecular formula C8H6F3N3, MW 201.15 g/mol) for analytical method development and quality control.
2-Amino-4-(trifluoromethyl)pyridine-3-acetonitrile (C8H6F3N3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Amino-4-(trifluoromethyl)pyridine-3-acetonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6F3N3 |
| Molecular Weight | 201.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
- 2-Amino-5-(trifluoromethyl)benzoimidazole (CAS 10057-46-2)
- 2-Amino-6-(trifluoromethyl)imidazo[1,2-a]pyridine (CAS 1005785-87-4)
- 3-Amino-5-(trifluoromethyl)pyridine-2-acetonitrile (CAS 1227494-35-0)
- 2-Amino-6-(trifluoromethyl)pyridine-4-acetonitrile (CAS 1227582-13-9)
- 6-Amino-2-(trifluoromethyl)pyridine-3-acetonitrile (CAS 1227582-14-0)
- 3-Amino-2-(trifluoromethyl)pyridine-4-acetonitrile (CAS 1227587-09-8)
- 2-Amino-6-(trifluoromethyl)pyridine-3-acetonitrile (CAS 1227598-80-2)
- 2-Amino-5-(trifluoromethyl)pyridine-3-acetonitrile (CAS 1228897-91-3)
Recommended Standards
- 2-Amino-5-(trifluoromethyl)pyridine-4-acetonitrile (CAS 1228898-09-6)
- 4-Ethynyl-2-(trifluoromethoxy)aniline (CAS 1233506-33-6)
- 2-Amino-3-(trifluoromethyl)pyridine-4-acetonitrile (CAS 1228898-08-5)
- 3-(Trifluoromethyl)-1H-pyrrolo[2,3-b]pyridin-4-amine (CAS 1255099-01-4)
- 1-(2,4-Dimethylphenyl)-3-(3,4-dimethylphenyl)propan-1-one (CAS 898779-35-6)
- 4-(<I>Z</I>-amino)cyclohexanol (CAS 16801-62-0)
- 2,4,5-Trifluorobenzoic Acid (CAS 446-17-3)
- Larotrectinib Impurity 16 (CAS 2699151-02-3)
- (R)-3-Amino-4-(2-chlorophenyl)butanoic acid (CAS 268734-28-7)
- 2-Methyl-4-(oxetan-3-yloxy)benzonitrile (CAS 1599807-43-8)
- 2-Methylglutaric acid (CAS 18069-17-5)
- 2-(2-Fluoro-5-methoxyphenyl)-2-hydroxyacetic acid (CAS 1214372-67-4)
- 2-Thiomethyl-4-thiomorpholinomethyl benzophenone (CAS 898782-55-3)
- Tirzepatide Impurity 21 X TFA Salt (CAS CATO-C4X-324021)
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