7-Amino-6-bromo-1,2,3,4-tetrahydroquinolin-2-one CAS 1232685-09-4

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 7-Amino-6-bromo-1,2,3,4-tetrahydroquinolin-2-one.

7-Amino-6-bromo-1,2,3,4-tetrahydroquinolin-2-one (CAS 1232685-09-4) is a high-purity analytical reference standard with the molecular formula C9H9BrN2O and a molecular weight of 241.08 g/mol.

The molecular framework of 7-Amino-6-bromo-1,2,3,4-tetrahydroquinolin-2-one (C9H9BrN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 7-Amino-6-bromo-1,2,3,4-tetrahydroquinolin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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