5-Amino-2,4-dichlorobenzene-1-sulfonamide CAS 4818-77-3
| CAS No. | 4818-77-3 |
| Molecular Formula | C6H6Cl2N2O2S |
| Molecular Weight | 241.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Amino-2,4-dichlorobenzene-1-sulfonamide (CAS 4818-77-3), molecular formula C6H6Cl2N2O2S and molecular weight 241.10 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 5-Amino-2,4-dichlorobenzene-1-sulfonamide is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 241.10 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H6Cl2N2O2S |
| Molecular Weight | 241.10 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 4-Amino-2,6-dichlorobenzene-1-sulfonamide (CAS 172514-47-5)
- 4-Amino-2,5-dichlorobenzenesulfonamide (CAS 42480-70-6)
- 4-amino-3,5-dichlorobenzenesulfonamide (CAS 22134-75-4)
- 7-Amino-6-bromo-1,2,3,4-tetrahydroquinolin-2-one (CAS 1232685-09-4)
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Recommended Standards
- 5-Bromobenzo[b]thiophene-2-carbaldehyde (CAS 7312-18-7)
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- 6-Bromo-4H-thiochromen-4-one (CAS 20076-75-9)
- 4,6-Dichloro-2-(methanesulfonylmethyl)pyrimidine (CAS 944058-99-5)
- Pyridazine hydrochloride (CAS 6164-80-3)
- 4-Hydroxy-6-(propan-2-yl)-2H-pyran-2-one (CAS 220809-37-0)
- N,2-dihydroxy-5-nitrobenzamide (CAS 61494-42-6)
- 5,6-Diaminopyrimidine-2,4-diol hydrochloride (CAS 53608-89-2)
- 2-Bromo-4′-fluoroacetophenone-2′,3′,5′,6′-d4 (CAS 1219803-30-1)
- (2S,3R,4S,5S)-5-((R)-1-Azido-2-(pivaloyloxy)ethyl)tetrahydrofuran-2,3,4-triyl tris(2,2-dimethylpropanoate) (CAS 226877-06-1)
- 7-Fluoro-8-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline (CAS 2818961-70-3)
- N-[3-(Allyloxy)phenyl]-2-bromoacetamide (CAS 99859-22-0)
- 3-(Aminomethyl)-N-cyclohexyl-N-ethylpyridin-2-amine (CAS 953723-82-5)
- Renin Inhibitor Peptide (CAS 50410-01-0)
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