1-(4-(o-Tolyl)thiazol-2-yl)guanidine CAS 123309-87-5

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(4-(o-Tolyl)thiazol-2-yl)guanidine.

1-(4-(o-Tolyl)thiazol-2-yl)guanidine (CAS 123309-87-5), molecular formula C11H12N4S and molecular weight 232.30 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 1-(4-(o-Tolyl)thiazol-2-yl)guanidine (C11H12N4S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 1-(4-(o-Tolyl)thiazol-2-yl)guanidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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