methyl 6-chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxylate CAS 1234615-81-6
| CAS No. | 1234615-81-6 |
| Molecular Formula | C9H15ClN2O2 |
| Molecular Weight | 218.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of methyl 6-chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxylate is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
methyl 6-chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxylate (CAS 1234615-81-6), molecular formula C9H15ClN2O2 and molecular weight 218.68 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, methyl 6-chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxylate (C9H15ClN2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 218.68 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H15ClN2O2 |
| Molecular Weight | 218.68 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related methyl Standards
- 4-Benzyl-6-chloro-2-methylpyrimidine (CAS 100565-30-8)
- 4-Chloro-1-(2,2-diethoxyethyl)-1h-pyrazole (CAS 1006334-37-7)
- 2-Chloro-N-(pyridin-4-ylmethyl)aniline (CAS 1019552-09-0)
- 2-Chloro-N-(pyridin-3-ylmethyl)aniline (CAS 1019624-08-8)
- 6-Chloro-4,4'-dimethyl-2,2'-bipyridine (CAS 1025763-34-1)
- methyl 6-chloro-1H-pyrrolo[3,2-b]pyridine-2-carboxylate (CAS 1083196-33-1)
- (2'-Chloro-[1,1'-biphenyl]-4-yl)methanol (CAS 109524-03-0)
- 4-Chloro-2-cyclobutylquinazoline (CAS 1095559-57-1)
Recommended Standards
- 6-Chloropyrazolo[1,5-a]pyridine-2-carboxylic acid methyl ester (CAS 1222709-26-3)
- methyl 4-chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxylate (CAS 1234616-82-0)
- 6-Chloro-N-(3-methylphenyl)-2-pyridinamine (CAS 1220019-91-9)
- (R)-(4-Chlorophenyl)(phenyl)methanol (CAS 123535-85-3)
- (S)-5-(Methyl-d3)-3-(trifluoromethyl)-7,8,9,10-tetrahydro-5H-pyrazino[1,2-a]pyrido[3,2-e]pyrazin-6(6aH)-one (CAS 2817669-32-0)
- Tert-butyl 2-[4-(hydroxymethyl)-1H-1,2,3-triazol-1-yl]acetate (CAS 1394041-94-1)
- Isobutyl (E)-2-methylbut-2-enoate (CAS 61692-84-0)
- 1-(tert-Butoxycarbonyl)-3-(pyridin-4-ylmethyl)piperidine-3-carboxylicacid (CAS 887344-19-6)
- 6-methyl-3-phenylimidazo[1,2-a]pyridine (CAS 1338248-70-6)
- 4,4-dimethoxycyclohexanol (CAS 112906-44-2)
- Orforglipron impurity 101 (CAS CATO-C4X-3234101)
- (R,E)-4-((6,7-Dihydroxy-3,7-dimethyloct-2-en-1-yl)oxy)-7H-furo[3,2-g]chromen-7-one (CAS 264234-05-1)
- 5'-O-DMt-thymidine 3'-o-succinate triethylammonium salt (CAS 402944-22-3)
- Tetrapeptide-30/Tegopep (CAS 1036207-61-0)
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