methyl 4-chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxylate CAS 1234616-82-0
| CAS No. | 1234616-82-0 |
| Molecular Formula | C9H15ClN2O2 |
| Molecular Weight | 218.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including methyl 4-chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxylate.
methyl 4-chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxylate (CAS 1234616-82-0) is a high-purity analytical reference standard with the molecular formula C9H15ClN2O2 and a molecular weight of 218.68 g/mol.
methyl 4-chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxylate (C9H15ClN2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures methyl 4-chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H15ClN2O2 |
| Molecular Weight | 218.68 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related methyl Standards
- 4-Benzyl-6-chloro-2-methylpyrimidine (CAS 100565-30-8)
- 4-Chloro-1-(2,2-diethoxyethyl)-1h-pyrazole (CAS 1006334-37-7)
- 2-Chloro-N-(pyridin-4-ylmethyl)aniline (CAS 1019552-09-0)
- 2-Chloro-N-(pyridin-3-ylmethyl)aniline (CAS 1019624-08-8)
- 6-Chloro-4,4'-dimethyl-2,2'-bipyridine (CAS 1025763-34-1)
- methyl 6-chloro-1H-pyrrolo[3,2-b]pyridine-2-carboxylate (CAS 1083196-33-1)
- (2'-Chloro-[1,1'-biphenyl]-4-yl)methanol (CAS 109524-03-0)
- 4-Chloro-2-cyclobutylquinazoline (CAS 1095559-57-1)
Recommended Standards
- methyl 6-chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxylate (CAS 1234615-81-6)
- (R)-(4-Chlorophenyl)(phenyl)methanol (CAS 123535-85-3)
- 6-Chloropyrazolo[1,5-a]pyridine-2-carboxylic acid methyl ester (CAS 1222709-26-3)
- 1-(4-Acetyl-1,4-diazepan-1-yl)-2-chloroethan-1-one (CAS 1247927-01-0)
- 3-(3,5-Dichlorophenyl)propiolic acid (CAS 1343152-27-1)
- 2-(4-Chlorophenyl)-2-phenylacetonitrile (CAS 4578-80-7)
- Potassium trifluoro(phenoxymethyl)borate (CAS 1027642-30-3)
- 1-benzyl-1H,2H,3H-imidazo[4,5-c]pyridin-2-one (CAS 61719-58-2)
- 3-Bromo-5-(trifluoromethoxy)benzene-1,2-diamine (CAS 1191922-50-5)
- 2-Bromo-3-(trifluoromethyl)benzoic acid (CAS 177420-63-2)
- (4-Methyl-1h-pyrazol-1-yl)methanol (CAS 146456-97-5)
- 1-Methyl-4-nitro-1H-indole-3-carbaldehyde (CAS 36728-90-2)
- (2S,3S,4R,5R)-2-(7-Acetamido-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-5-(acetoxymethyl)tetrahydrofuran-3,4-diyl diacetate (CAS 13351-66-1)
- [D-Ser6]-Semaglutide (CAS CATO-C4X-2226287)
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