5-Bromo-4-fluoro-2-iodo-1H-pyrrolo[2,3-b]pyridine CAS 1234616-48-8
| CAS No. | 1234616-48-8 |
| Molecular Formula | C7H3BrFIN2 |
| Molecular Weight | 340.92 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
5-Bromo-4-fluoro-2-iodo-1H-pyrrolo[2,3-b]pyridine (CAS 1234616-48-8) is a high-purity analytical reference standard with the molecular formula C7H3BrFIN2 and a molecular weight of 340.92 g/mol.
Owing to a nitrile group, fluorine/bromine/iodine substitution, an aromatic ring system, 5-Bromo-4-fluoro-2-iodo-1H-pyrrolo[2,3-b]pyridine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 340.92 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C7H3BrFIN2 |
| Molecular Weight | 340.92 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Br/I-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 7-Bromo-4-fluoro-3-iodo-1H-indazole (CAS 1000342-12-0)
- 5-Bromo-4-fluoro-3-iodo-1H-indazole (CAS 1082041-88-0)
- 7-Bromo-4-fluoro-3-iodo-1H-pyrrolo[2,3-c]pyridine (CAS 1190320-82-1)
- 6-Bromo-5-fluoro-3-iodo-1H-indazole (CAS 1286734-77-7)
- 5-Bromo-7-fluoro-3-iodo-1H-indazole (CAS 1352398-23-2)
- 4-Bromo-6-fluoro-3-iodo-1H-indazole (CAS 887567-87-5)
- 5-Bromo-6-fluoro-3-iodo-1H-indazole (CAS 633335-82-7)
- 6-Bromo-3-fluoro-8-iodoimidazo[1,2-a]pyridine (CAS 2387598-54-9)
Recommended Standards
- 2-Amino-5-bromo-6-fluoro-3-iodobenzonitrile (CAS 1000577-88-7)
- 2-Amino-3-bromo-6-fluoro-5-iodobenzonitrile (CAS 1000577-79-6)
- 4,6-Dibromo-3-hydroxy-2-nitrobenzoic acid (CAS 160911-18-2)
- 6-Bromo-4-fluoro-3-iodo-1H-indazole (CAS 887568-00-5)
- 1-(Chloromethyl)-4-(4-(trifluoromethyl)phenoxy)benzene (CAS 111818-34-9)
- 2-tert-butyl-4-methyl-1,3-thiazole-5-carboxylic acid (CAS 427896-41-1)
- (2-Amino-2-phenylethoxy)benzene hydrochloride (CAS 16797-05-0)
- 5-acetyl-6-methyl-4-thioxo-3,4-dihydropyrimidin-2(1H)-one (CAS 90151-12-5)
- 3-Methyl-6-nitrocinnolin-4(1h)-one (CAS 500590-07-8)
- 6-Methylpyridine-2,3-dicarboxylic Acid (CAS 53636-70-7)
- 4’-Bromo-3-iodo-1,1’-biphenyl (CAS 130201-21-7)
- Fmoc-N-Et-Phe(4-Me)-OH (CAS 2490159-62-9)
- 6,7-Dihydro-1H-cyclopenta[b]pyridine-2,4(3H,5H)-dione (CAS 337960-53-9)
- Myosin Kinase Inhibiting Peptide (CAS 119386-39-9)
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