1-(Propylsulfonyl)-4-(2,2,2-trifluoroethyl)piperazine CAS 1235040-59-1
| CAS No. | 1235040-59-1 |
| Molecular Formula | C9H17F3N2O2S |
| Molecular Weight | 274.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(Propylsulfonyl)-4-(2,2,2-trifluoroethyl)piperazine (CAS 1235040-59-1), molecular formula C9H17F3N2O2S and molecular weight 274.30 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, 1-(Propylsulfonyl)-4-(2,2,2-trifluoroethyl)piperazine is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 274.30 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(Propylsulfonyl)-4-(2,2,2-trifluoroethyl)piperazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H17F3N2O2S |
| Molecular Weight | 274.30 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Propylsulfonyl Standards
- 4-Methyl-6-(propylsulfonyl)quinolin-2(1H)-one (CAS 1207858-39-6)
- Ethyl 4-(propylsulfonyl)piperazine-1-carboxylate (CAS 1132825-82-1)
- 3-(Propylsulfonyl)pyridine-2-sulfonamide (CAS 117670-95-8)
- 4-(Propylsulfonyl)-1-naphthaldehyde (CAS 1394021-12-5)
- 2-(Propylsulfonyl)thieno[3,2-d][1,2,3]diazaborinin-1(2H)-ol (CAS 67398-10-1)
- 1-(Propylsulfonyl)-4-(pyridin-2-yl)piperidine-4-carbonitrile (CAS 866559-82-2)
- 2-(Propylsulfonyl)-1,2,3,4-tetrahydroisoquinolin-7-amine (CAS 1018288-47-5)
- 1-(Propylsulfonyl)-1,2,3,4-tetrahydroquinolin-6-amine (CAS 927996-21-2)
Recommended Standards
- (S)-2-(6-Hydroxyquinolin-2-yl)-4,5-dihydrothiazole-4-carboxylic acid (CAS 122364-83-4)
- 1-(5-Cyanothiazol-2-yl)-3-(4-methoxyphenyl)urea (CAS 1251710-40-3)
- 7-(Methylsulfonyl)-1-phenyl-1H-imidazo[4,5-d]pyridazine (CAS 121433-41-8)
- 3-Ethyl-6-(thiophen-2-yl)isoxazolo[5,4-b]pyridine-4-carboxylic acid (CAS 1263212-63-0)
- 1',5',6',7'-Tetrahydrospiro[cyclopentane-1,4'-cyclopenta[d]pyrimidine]-2'(3'H)-thione (CAS 5778-25-6)
- 3-Chloro-5,7-dihydro-6H-pyrrolo[2,3-b]pyrazin-6-one (CAS 1823922-40-2)
- 262601-45-6 N-Ethylethan(~15~N)amine--hydrogen chloride (1/1) DTXSID90583933 (CAS 262601-45-6)
- N-Nitroso Verapamil Impurity-2 (CAS CATO-C4X-177841)
- Baxdrostat Impurity 20 (CAS 1428652-30-5)
- 3-Amino-4-iodobenzotrifluoride (CAS 105202-02-6)
- 2,5-Dimethoxy-2-methyltetrahydrofuran (CAS 58518-63-1)
- 2-(4-(Difluoromethoxy)phenyl)propanenitrile (CAS 1096790-41-8)
- 2-(2-Methoxycarbonyl-4-nitrophenyl)-5-nitrobenzoic acid (CAS 710327-97-2)
- Tirzepatide Impurity 1 (CAS 2460751-66-8)
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