(4R,5R)-2-chloro-3,4-dimethyl-2,5-diphenyl-1,3,2-oxazasilolidine CAS 1236123-69-5
| CAS No. | 1236123-69-5 |
| Molecular Formula | C16H18ClNOSi |
| Molecular Weight | 303.86 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(4R,5R)-2-chloro-3,4-dimethyl-2,5-diphenyl-1,3,2-oxazasilolidine (CAS 1236123-69-5), molecular formula C16H18ClNOSi and molecular weight 303.86 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (4R,5R)-2-chloro-3,4-dimethyl-2,5-diphenyl-1,3,2-oxazasilolidine (C16H18ClNOSi) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H18ClNOSi |
| Molecular Weight | 303.86 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 2-Chloro-N-(5-nonyl-1,3,4-thiadiazol-2-yl)acetamide (CAS 565168-90-3)
- 4-Chlorophenylzinc iodide 0.5 M in Tetrahydrofuran (CAS 151073-70-0)
- 2,2,3,3-Tetrachloro-1,1,1,4,4,4-hexafluorobutane (CAS 375-34-8)
- 3-Chlorophenylzinc iodide 0.5 M in Tetrahydrofuran (CAS 186000-42-0)
- (R)-3-(Furan-2-yl)piperazin-2-one (CAS 1240590-60-6)
- 1-Bromo-4-butoxy-2-fluorobenzene (CAS 155854-29-8)
- 2-(1-(tert-Butoxycarbonyl)pyrrolidin-2-yl)acetic Acid (CAS 194154-91-1)
- cis-3-hydroxycyclopentanecarboxylic acid (CAS 55843-47-5)
- Tert-butyl 4-methyl-4-(methylamino)piperidine-1-carboxylate (CAS 1420956-33-7)
- 2-Chloropyrimidine-5-boronic Acid (CAS 1003845-06-4)
- m-Tolylmagnesium Bromide, 1.0 M solution in THF (CAS 28987-79-3)
- 2,2,2-Trifluoro-1-(5-(p-tolyl)-1H-pyrrol-2-yl)ethan-1-one (CAS 113768-63-1)
- 6-(2-Methoxyethoxy)-1H-indol-5-ol (CAS 1622205-59-7)
- Anti-Inflammatory Peptide 2 (CAS 118850-72-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com