6-(Bromomethyl)-2-chloroquinoline CAS 123637-77-4
| CAS No. | 123637-77-4 |
| Molecular Formula | C10H7BrClN |
| Molecular Weight | 256.53 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
6-(Bromomethyl)-2-chloroquinoline (CAS 123637-77-4) is a high-purity analytical reference standard with the molecular formula C10H7BrClN and a molecular weight of 256.53 g/mol.
The molecular framework of 6-(Bromomethyl)-2-chloroquinoline (C10H7BrClN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H7BrClN |
| Molecular Weight | 256.53 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromomethyl Standards
- 2-(Bromomethyl)-7-chloroquinoline (CAS 115104-25-1)
- 6-(Bromomethyl)-4-chloroquinoline (CAS 141848-62-6)
- 3-(Bromomethyl)-2-chloroquinoline (CAS 35740-82-0)
- 3-(Bromomethyl)-4-chloroquinoline (CAS 397322-26-8)
- 3-(Bromomethyl)-7-chloroisoquinoline (CAS 234098-38-5)
- 6-(Bromomethyl)-1-chloroisoquinoline (CAS 234109-25-2)
- 7-(Bromomethyl)-1-chloroisoquinoline (CAS 209285-92-7)
- 8-(bromomethyl)-5-chloroquinoline (CAS 88474-19-5)
Recommended Standards
- 5-Bromo-3-chloro-1-methylisoquinoline (CAS 1215767-97-7)
- 5-Bromo-1-chloro-6-methylisoquinoline (CAS 1245647-25-9)
- 5-Bromo-1-chloro-3-methylisoquinoline (CAS 1206984-59-9)
- 6-Bromo-1-chloro-4-methylisoquinoline (CAS 1256794-60-1)
- 6H-Benzo[c]chromen-10-ol (CAS 1068441-36-0)
- 2-Amino-2-(4-nitrophenyl)acetic acid (CAS 5407-25-0)
- 5-Bromo-N1-isopropyl-1,2-benzenediamine (CAS 1038408-35-3)
- 7,8-Dihydro-5(6H)-quinazolinone (CAS 21599-28-0)
- Ethyl 5-fluoro-8-methyl-4-(methylamino)quinoline-3-carboxylate (CAS 1283467-13-9)
- [(3S)-3-Aminotutyl](methyl)amine hydrochloride (CAS 1379437-81-6)
- 2-(2-Chlorophenoxy)-2-methylpropanoic acid (CAS 17413-79-5)
- L-Ornithine-2,3,3,4,4,5,5-d7 hydrochloride (CAS 2483831-57-6)
- Bupivacaine Impurity 40 (CAS CATO-C4X-148240)
- Semaglutide impurity 42 (CAS CATO-C4X-222642)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com