6-(Bromomethyl)-1-chloroisoquinoline CAS 234109-25-2
| CAS No. | 234109-25-2 |
| Molecular Formula | C10H7BrClN |
| Molecular Weight | 256.53 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-(Bromomethyl)-1-chloroisoquinoline (C10H7BrClN) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 6-(Bromomethyl)-1-chloroisoquinoline (CAS 234109-25-2), a certified reference material (molecular formula C10H7BrClN, MW 256.53 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H7BrClN |
| Molecular Weight | 256.53 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2023 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromomethyl Standards
- 2-(Bromomethyl)-7-chloroquinoline (CAS 115104-25-1)
- 6-(Bromomethyl)-2-chloroquinoline (CAS 123637-77-4)
- 6-(Bromomethyl)-4-chloroquinoline (CAS 141848-62-6)
- 3-(Bromomethyl)-2-chloroquinoline (CAS 35740-82-0)
- 3-(Bromomethyl)-4-chloroquinoline (CAS 397322-26-8)
- 3-(Bromomethyl)-7-chloroisoquinoline (CAS 234098-38-5)
- 7-(Bromomethyl)-1-chloroisoquinoline (CAS 209285-92-7)
- 8-(bromomethyl)-5-chloroquinoline (CAS 88474-19-5)
Recommended Standards
- 4-Bromo-6-chloro-8-methylquinoline (CAS 927800-42-8)
- 6-Bromo-1-(chloromethyl)isoquinoline (CAS 2092723-65-2)
- 4-Bromo-2-chloronaphthalen-1-amine (CAS 51670-71-4)
- 6-Bromo-2-chloro-4-methylquinoline (CAS 3913-19-7)
- Alpha-(4-methoxyphenyl)morpholine-4-acetonitrile (CAS 15190-13-3)
- n-Ethyl-2-methylpyridin-3-amine (CAS 1346544-43-1)
- 6-Bromo-8-methyl-4-(trifluoromethyl)quinolin-2(1H)-one (CAS 1375066-09-3)
- 2-(3-Fluorophenyl)-6-(trifluoromethyl)nicotinonitrile (CAS 935520-42-6)
- Atosiban Impurity 3 (CAS CATO-C4X-22933)
- 2-(3-Methylbut-2-en-2-yl)-4,5,6,7-tetrahydrobenzofuran (CAS 89880-44-4)
- tert-Butyl(2-chloro-3-fluorophenoxy)dimethylsilane (CAS 1881296-32-7)
- Naproxen Impurity 48 (CAS CATO-C4X-170848)
- Ethyl 4-{[(4-chlorophenyl)methyl]amino}-1-methyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate (CAS 1221715-35-0)
- Tirzepatide Impurity 35 (CAS CATO-C4X-324035)
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