3,3-Difluoropiperidin-4-ol CAS 1239596-54-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1239596-54-3
Molecular FormulaC5H9F2NO
Molecular Weight137.13 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3,3-Difluoropiperidin-4-ol CAS 1239596-54-3 chemical structure

Description

The molecular framework of 3,3-Difluoropiperidin-4-ol (C5H9F2NO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

3,3-Difluoropiperidin-4-ol (CAS 1239596-54-3), molecular formula C5H9F2NO and molecular weight 137.13 g/mol, is a CATO reference standard with documented purity and traceability.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC5H9F2NO
Molecular Weight137.13 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)1.0
CAS Registry Year (est.)1990
Halogen ContentF-containing
Nitrogen Atoms1

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