1-Benzyl-3,3-difluoropiperidin-4-ol CAS 1239596-53-2
| CAS No. | 1239596-53-2 |
| Molecular Formula | C12H15F2NO |
| Molecular Weight | 227.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-Benzyl-3,3-difluoropiperidin-4-ol (C12H15F2NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
1-Benzyl-3,3-difluoropiperidin-4-ol (CAS 1239596-53-2) is a high-purity analytical reference standard with the molecular formula C12H15F2NO and a molecular weight of 227.25 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-Benzyl-3,3-difluoropiperidin-4-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H15F2NO |
| Molecular Weight | 227.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Benzyl Standards
- 1-Benzyl-3,3-difluoropiperidin-4-amine (CAS 1039741-55-3)
- 5-(4,4-Difluoropiperidin-1-yl)picolinaldehyde (CAS 1707365-72-7)
- 5-(3,3-Difluoropiperidin-1-yl)nicotinaldehyde (CAS 1707581-12-1)
- 3-(3,3-Difluoropiperidin-1-yl)picolinaldehyde (CAS 1707581-13-2)
- 3-(3,3-Difluoropiperidin-1-yl)isonicotinaldehyde 1707605-03-5 (CAS 1707605-03-5)
- 5-(4,4-Difluoropiperidin-1-yl)nicotinaldehyde (CAS 1707605-04-6)
- 3-(4,4-Difluoropiperidin-1-yl)picolinaldehyde (CAS 1707605-05-7)
- 2-(3,3-Difluoropiperidin-1-yl)nicotinaldehyde (CAS 1774895-41-8)
Recommended Standards
- 4-(4-(Difluoromethoxy)phenyl)piperidine (CAS 1211530-65-2)
- (1-(2,5-Difluorobenzyl)pyrrolidin-3-yl)methanol (CAS 1250270-58-6)
- 4-(Benzyloxy)-3,3-difluoropiperidine (CAS 1206540-59-1)
- 3-(3,4-Difluoro-5-methoxyphenyl)piperidine (CAS 1260885-33-3)
- 5-Chloro-3-(pyridin-2-yl)-1,2,4-thiadiazole (CAS 887623-91-8)
- 3-[(benzyloxy)methyl]-2-fluorocyclobutan-1-one (CAS 890529-23-4)
- o-(Pyridin-2-ylmethyl)hydroxylamine (CAS 37756-48-2)
- n-(3-Aminopropyl)-2-methoxyacetamide (CAS 1016679-58-5)
- D,L-Buthionine-(S,R)-sulfoximine (CAS 5072-26-4)
- Empagliflozin impurity 213 (CAS CATO-C4X-1065213)
- Bortezomib Impurity 33 (CAS 73058-37-4)
- 2-(1H-Benzo[d]imidazol-2-yl)benzohydrazide (CAS 148438-23-7)
- 3-Fluoro-4-(4-methyl-1H-pyrazol-1-yl)aniline hydrochloride (CAS 1332528-59-2)
- Tirzepatide Impurity 49 (CAS CATO-C4X-324049)
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