Hydrocodone EP Impurity D CAS 124-90-3
| CAS No. | 124-90-3 |
| Molecular Formula | C18H21NO4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Hydrocodone EP Impurity D is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 351.83 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Hydrocodone EP Impurity D (CAS 124-90-3), a pharmacopoeial impurity reference standard (molecular formula C18H21NO4HCl, MW 351.83 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Hydrocodone EP Impurity D under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H21NO4 HCl |
| Molecular Weight | 351.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Hydrocodone Standards
- Hydrocodone-D6 (CAS 1007844-38-3)
- Hydrocodone-d3 (CAS 1007854-30-9)
- Hydrocodone-D3 (CAS 136765-36-1)
- Hydrocodone (+)-bitartrate salt (CAS 143-71-5)
- Hydrocodone Hydrochloride (CAS 25968-91-6)
- Hydrocodone Bitartrate CII (100 mg) (CAS 34195-34-1)
- Hydrocodone Hydrogen Tartrate Hydrate - Impurity G (CAS 41714-53-8)
- Hydrocodone Related Compound A CII (70 mg) (4-hydroxy-3-methoxy-17-methylmorphinan-6-one) (CAS 847-86-9)
Recommended Standards
- Sparfloxacin Impurity 4 (CAS CATO-C4X-21134)
- Upadacitinib Impurity 164 (CAS CATO-C4X-2405164)
- Rivaroxaban Impurity 203 (CAS CATO-C4X-1090203)
- (E)-6-methyl-2-(4-styrylphenyl)benzo[b]thiophene (CAS 22786-00-1)
- 5,6-Difluoro-3,4-dihydronaphthalen-1(2H)-one (CAS 939043-53-5)
- 2-(Aminomethyl)-3-(difluoromethyl)-4-fluoropyridine-6-carboxaldehyde (CAS 1805615-18-2)
- 1-((1,2,3,4-Tetrahydronaphthalen-2-yl)amino)propan-2-ol (CAS 854901-18-1)
- Methyl 2-(2,5-difluoropyridin-4-yl)acetate (CAS 1803789-59-4)
- 1-Chloro-6-isopropylisoquinoline (CAS 630422-59-2)
- Influenza PR8 Hemagglutinin Peptide (110-119) (H-6312.0005) (CAS 132031-50-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com